北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
6期
15-16
,共2页
鲍曼不动杆菌%肺炎%药物敏感性
鮑曼不動桿菌%肺炎%藥物敏感性
포만불동간균%폐염%약물민감성
Acinetobacter baumannii%Pneumonia%Drug susceptibility
目的:分析和总结鲍曼不动杆菌肺炎的临床特点和对抗生素敏感性的分布情况;方法:对41例鲍曼不动杆菌肺炎的临床资料进行统计分析,测定该菌的药物敏感性;结果:41例中,老年患者37例(90.24%),患有基础疾病患者41例(100%),其中,11例(26.83%)有慢性阻塞性肺病病史,25例(60.98%)存在低蛋白血症;院外感染14例(34.15%),院内感染27例(65.85%)。临床表现主要为咳嗽41例(100%),咳痰41例(100%),发热26例(63.41%),呼吸困难28例(68.29%);胸部X线均呈现程度不等肺部浸润阴影。药敏检测表明,除了对阿米卡星、高剂量的庆大霉素、头孢吡肟、氨苄西林/舒巴坦比较敏感外(58.49%~41.94%),该菌广泛耐药。结论:鲍曼不动杆菌肺炎好发于老年、有基础疾病及免疫功能低下者,及早选择可能敏感的抗生素及进行细菌药敏检测将有益于改善预后。
目的:分析和總結鮑曼不動桿菌肺炎的臨床特點和對抗生素敏感性的分佈情況;方法:對41例鮑曼不動桿菌肺炎的臨床資料進行統計分析,測定該菌的藥物敏感性;結果:41例中,老年患者37例(90.24%),患有基礎疾病患者41例(100%),其中,11例(26.83%)有慢性阻塞性肺病病史,25例(60.98%)存在低蛋白血癥;院外感染14例(34.15%),院內感染27例(65.85%)。臨床錶現主要為咳嗽41例(100%),咳痰41例(100%),髮熱26例(63.41%),呼吸睏難28例(68.29%);胸部X線均呈現程度不等肺部浸潤陰影。藥敏檢測錶明,除瞭對阿米卡星、高劑量的慶大黴素、頭孢吡肟、氨芐西林/舒巴坦比較敏感外(58.49%~41.94%),該菌廣汎耐藥。結論:鮑曼不動桿菌肺炎好髮于老年、有基礎疾病及免疫功能低下者,及早選擇可能敏感的抗生素及進行細菌藥敏檢測將有益于改善預後。
목적:분석화총결포만불동간균폐염적림상특점화대항생소민감성적분포정황;방법:대41례포만불동간균폐염적림상자료진행통계분석,측정해균적약물민감성;결과:41례중,노년환자37례(90.24%),환유기출질병환자41례(100%),기중,11례(26.83%)유만성조새성폐병병사,25례(60.98%)존재저단백혈증;원외감염14례(34.15%),원내감염27례(65.85%)。림상표현주요위해수41례(100%),해담41례(100%),발열26례(63.41%),호흡곤난28례(68.29%);흉부X선균정현정도불등폐부침윤음영。약민검측표명,제료대아미잡성、고제량적경대매소、두포필우、안변서림/서파탄비교민감외(58.49%~41.94%),해균엄범내약。결론:포만불동간균폐염호발우노년、유기출질병급면역공능저하자,급조선택가능민감적항생소급진행세균약민검측장유익우개선예후。
Objective:To analyze and summarize the clinical features and distribution of antibiotic susceptibility of Acinetobacter baumannii pneumonia .Methods:We statistically analyzed the clinical data of fifty-two cases of Acinetobacter baumannii and determined drug susceptibility of this bactiria .Results :37 out of 41(that is 90.24%)cases were old age patients.100%patients were with underlying disease,while 11(26.83%)cases had chronic obstructive pulmonary disease history,25(60.98%) cases were with hypoproteinaemia .Out-of hospital infection and nosocomial infection were 14(34.15%)cases and 27(65.85%),respectively. The cliniccal symptoms were mainly cough, expectoration(100%),26(63.41%) cases had fever,28cases(68.29%)had dyspnea. Chest X-ray showed different-degree shadow on lungs.Besides Amikacin、Gentamicin with high dose、cefepime、ampicillin \sulbactam were susceptive (58.49%~41.94%),the drug susceptibility test showed.Conclusion :The risk factors of Acinetobacter baumannii pneumonia were ageing,underlying diseases and immunodeficiency.Early choosing susceptive antibiotics and drug sensitivity test would improve the prognosis.