CAJ | 학술논문

目的：探讨功能性胃肠病伴自主神经紊乱的临床意义及诊疗方法。方法选取2005年4月～2013年11月我院门诊及住院的伴随有自主神经紊乱的功能性胃肠病患者400例，对自主神经紊乱的症状进行统计、分析，按照严重程度分为轻、中、重三级，并与焦虑/抑郁评分进行对比。所有患者随机分为治疗组与对照组，对治疗组患者按照不同程度进行个体化、阶梯式治疗；对照组患者则仅进行对症处理。所有病例至少随访半年。结果个体化、阶梯式治疗效果明显优于对照组仅进行对症处理者，两组比较治疗效果有显著性差异（P＜0.05）。结论自主神经紊乱是功能性胃肠病的重要和常见的并发症，不同患者严重程度不同，且与焦虑/抑郁情绪有密切关系，应该予以恰当的个体化治疗，按紊乱程度进行阶梯式治疗，效果良好。当治疗好转时，功能性胃肠病也有相应好转。
목적：탐토공능성위장병반자주신경문란적림상의의급진료방법。방법선취2005년4월～2013년11월아원문진급주원적반수유자주신경문란적공능성위장병환자400례，대자주신경문란적증상진행통계、분석，안조엄중정도분위경、중、중삼급，병여초필/억욱평분진행대비。소유환자수궤분위치료조여대조조，대치료조환자안조불동정도진행개체화、계제식치료；대조조환자칙부진행대증처리。소유병례지소수방반년。결과개체화、계제식치료효과명현우우대조조부진행대증처리자，량조비교치료효과유현저성차이（P＜0.05）。결론자주신경문란시공능성위장병적중요화상견적병발증，불동환자엄중정도불동，차여초필/억욱정서유밀절관계，응해여이흡당적개체화치료，안문란정도진행계제식치료，효과량호。당치료호전시，공능성위장병야유상응호전。
Objective To discuss the clinical significance of functional gastrointestinal disorder associated with autonomic nervous dysfunction and the diagnosis and treatment methods. Methods 400 cases of patients with functional gastrointestinal diseases associated with autonomic nervous dysfunction which received outpatient service or were hospitalized in our hospital from April 2005 to November 2005 were selected. The statistics and analysis of symptoms and signs of the autonomic nervous dysfunction were carried out. And according to the severity degree,the symptoms and signs were divided into three levels of light, medium and heavy and compared with anxiety/depression score.All patients were randomly divided into treatment group and control group,and individualized and stepwise treatment was used for the patients in the treatment group according to the different degrees; while only symptomatic treatment was used for the patients in the control group. All the cases were followed up for at least six months. Results The effect of individualized and stepwise treatment was better than the symptomatic treatment in the control group with significant difference(P < 0.05). Conclusion Autonomic nervous dysfunction is an important and common complication of functional gastrointestinal disease. Different patients have different severity degrees, which is closely related to the anxiety/depression emotion.Therefore,the individualized treatment should be used as well as the stepwise treatment according to the dysfunction degree to produce a good clinical effect.The condition of functional gastrointestinal disease will be improved with the corresponding improvement of treatment.