CAJ | 학술논문

目的：探讨异维A酸联合复方多黏菌素B软膏治疗中重度痤疮的临床效果。方法选择中重度痤疮患者60例为研究对象，随机分为研究组和对照组各30例，研究组联合异维A酸和复方多黏菌素B软膏治疗，对照组单用异维A酸治疗，比较两组患者的临床治疗效果。结果研究组总效率显著高于对照组（P＜0.01），平均起效时间短于对照组（P＜0.01）。结论异维A酸联合复方多粘菌素B软膏治疗中重度痤疮具有较好的临床疗效，并且起效快，不良反应少，值得临床推广。
목적：탐토이유A산연합복방다점균소B연고치료중중도좌창적림상효과。방법선택중중도좌창환자60례위연구대상，수궤분위연구조화대조조각30례，연구조연합이유A산화복방다점균소B연고치료，대조조단용이유A산치료，비교량조환자적림상치료효과。결과연구조총효솔현저고우대조조（P＜0.01），평균기효시간단우대조조（P＜0.01）。결론이유A산연합복방다점균소B연고치료중중도좌창구유교호적림상료효，병차기효쾌，불량반응소，치득림상추엄。
Objective To discuss the clinical efficacy of acutane combined with compound much slime molds element B ointment for moderate to severe acne. Methods Selected 60 cases with moderate to severe acne were divided into study group and control group.Study group was treated by acutane combined with compound much slime molds element B ointment, and control group was treated by acutane.Clinical efficacy of two groups was compared. Results Total efficacy of study group was higher than that of control group(P < 0.01).And onset time was shorter than that of control group(P<0.01). Conclusion Acutane combined with compound much slime molds element B ointment for moderate to severe acne shows better clinical efficacy, less complications, and worthy of spreading in clinical practice.