CAJ | 학술논문

目的：探讨九味镇心颗粒联合经颅磁刺激对广泛性焦虑(GAD)的治疗作用及安全性。方法68例 GAD患者随机分为两组，对照组33例，口服九味镇心颗粒，治疗组35例，在口服九味镇心颗粒的同时，加用经颅磁刺激治疗。疗程4周，两组基础治疗相同，均进行心理护理、疏导及支持治疗。以汉密尔顿焦虑量表(H AMA)对患者的焦虑程度及改善状况进行评定，并将两组疗效和安全性作对比。结果 HAMD评分两组治疗前后对比，差异均有统计学意义(P<0.05)，治疗后两组间比较差异有统计学意义(P<0.05)；总有效率治疗组88.57%，对照组78.79%，两组比较差异有统计学意义(P<0.05)；不良反应发生率两组比较无统计学意义。结论九味镇心颗粒联合经颅磁刺激治疗 GAD安全有效。
목적：탐토구미진심과립연합경로자자격대엄범성초필(GAD)적치료작용급안전성。방법68례 GAD환자수궤분위량조，대조조33례，구복구미진심과립，치료조35례，재구복구미진심과립적동시，가용경로자자격치료。료정4주，량조기출치료상동，균진행심리호리、소도급지지치료。이한밀이돈초필량표(H AMA)대환자적초필정도급개선상황진행평정，병장량조료효화안전성작대비。결과 HAMD평분량조치료전후대비，차이균유통계학의의(P<0.05)，치료후량조간비교차이유통계학의의(P<0.05)；총유효솔치료조88.57%，대조조78.79%，량조비교차이유통계학의의(P<0.05)；불량반응발생솔량조비교무통계학의의。결론구미진심과립연합경로자자격치료 GAD안전유효。
Objective To probe into the effect Jiuuer Zhenxin(JZP)particles combined with transcranial magnetic stimulation ea-sing on generalized anxiety.Methods Sixty eight patients were randomly divided into two groups:Control group(n=33)treated with Jiu Wer Zhen xin particles JZP and observation group(n=35)treated with(JZP)combined with transcranial magnetic stimula-tion.Hamilton anxiety scale and the side effects scale of the two groups were recorded and compared pre and post treatment.Re-sults Compared with the pre treatment,there were significant differences in Hamilton anxiety marks in both groups after treat-ment.There was significant differences in overall response rate between two groups,and no significant differences in side effects be-tween two groups.Conclusion JZP combined with transcranial magnetic stimulation was effective in the treatment of generalized anx-iety disorder with better effect and slight side effect.