CAJ | 학술논문

　　目的对穿心莲药材的有效成分进行定性定量鉴别，对水分、总灰分、酸不溶性灰分、浸出物及重金属含量进行定量测定，进一步完善穿心莲药材的质量标准。方法采用薄层色谱法对穿心莲中的穿心莲内酯和脱水穿心莲内酯进行定性鉴别，高效液相色谱法进行定量测定，常规检查项目按2010年版《中华人民共和国药典》(一部)附录Ⅸ A杂质检查法、Ⅸ H水分测定法中的烘干法、附录Ⅸ K灰分测定法、附录Ⅹ A浸出物测定法及Ⅸ E重金属检查法测定。结果10批穿心莲样品中穿心莲内酯和脱水穿心莲内酯及醇溶性浸出物含量均符合我国药典规定的标准。结论所建立的方法简便、准确，能作为质量标准以控制穿心莲药材的质量。
　　목적대천심련약재적유효성분진행정성정량감별，대수분、총회분、산불용성회분、침출물급중금속함량진행정량측정，진일보완선천심련약재적질량표준。방법채용박층색보법대천심련중적천심련내지화탈수천심련내지진행정성감별，고효액상색보법진행정량측정，상규검사항목안2010년판《중화인민공화국약전》(일부)부록Ⅸ A잡질검사법、Ⅸ H수분측정법중적홍간법、부록Ⅸ K회분측정법、부록Ⅹ A침출물측정법급Ⅸ E중금속검사법측정。결과10비천심련양품중천심련내지화탈수천심련내지급순용성침출물함량균부합아국약전규정적표준。결론소건립적방법간편、준학，능작위질량표준이공제천심련약재적질량。
Objective To improve the quality standard of Andrographis Herba through determination of effective components, moisture, total ashes, acid insoluble ashes, extracts and heavy metals. Methods TLC and HPLC were used for qualitative and quantitative identification of andrographolide and dehydroandrograpolide in Andrographis Herba. Routine examinations were based on the procedures recorded in the Appendix Ⅸ A, Ⅸ H, Ⅸ K, ⅩA and Ⅸ E of Chinese Pharmacopoeia (2010), for foreign matter, moisture, ashes, extracts determination and heavy metal test respectively. Results Total content of andrographolide and dehydroandrographolide, extractives (70% ethanol) all complied with Chinese pharmacopoeia. Conclusion The established method was simple, accurate and can be used as the quality standard for the quality control of Andrographis Herba.