CAJ | 학술논문

目的：探讨对支气管镜毛刷标本进行液基薄层细胞学制片技术( LCT)在肺癌细胞诊断中的应用价值。方法收集252例肺癌患者的支气管镜刷检标本,同时进行LCT和直接涂片法检测,比较两种方法的涂片质量及诊断的阳性率。结果 LCT检测的标本切片质量高,LCT诊断肺癌的敏感度为58.33%。直接涂片法诊断肺癌的敏感度为33.19%。 LCT的敏感度高于直接涂片法(P<0．05)。结论 LCT液基薄层细胞学制片技术在支气管镜刷检细胞学标本制片质量及诊断准确性明显高于传统涂片方法,支气管镜刷检标本的LCT检测可推广应用于临床。
목적：탐토대지기관경모쇄표본진행액기박층세포학제편기술( LCT)재폐암세포진단중적응용개치。방법수집252례폐암환자적지기관경쇄검표본,동시진행LCT화직접도편법검측,비교량충방법적도편질량급진단적양성솔。결과 LCT검측적표본절편질량고,LCT진단폐암적민감도위58.33%。직접도편법진단폐암적민감도위33.19%。 LCT적민감도고우직접도편법(P<0．05)。결론 LCT액기박층세포학제편기술재지기관경쇄검세포학표본제편질량급진단준학성명현고우전통도편방법,지기관경쇄검표본적LCT검측가추엄응용우림상。
Objective To explore the clinical value of liquid-based cytology test ( LCT ) in cytological screening of bronchial brushing for the diagnosis of lung cancer. Methods The bronchial brushing specimens of 252 patients who were diagnosed as lung cancer were collected. The diagnostic sensitivity and cytological findings of LCT were compared with those of conventional smear ( CS) method for diagnosing lung cancer. Results LCT slides showed decreased areas of cell monolayers. LCT had a significantly higher diagnostic sensitivity for lung cancer (58. 33%) than CS method did (33. 19%, P<0. 05). Conclusion LCT in cytological screening of bronchial brushing has higher diagnostic value of lung cancer and it can be easily performed.