临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2014年
7期
1298-1299,1300
,共3页
目的：探讨Fascin蛋白在肺癌患者血清中的表达及临床意义。方法检测61例肺癌患者及20例肺部良性病变患者血清中Fascin蛋白阳性表达率。结果 NSCLC患者血清中Fascin阳性率(37．25%)明显高于SCLC(7．69%)患者及肺部良性病变患者(5%)；在不同临床分期的NSCLC患者中,Fascin阳性率差异有统计学意义。结论 Fascin在NSCLC患者中表达提高,且与分期相关,有一定判断预后的价值。
目的：探討Fascin蛋白在肺癌患者血清中的錶達及臨床意義。方法檢測61例肺癌患者及20例肺部良性病變患者血清中Fascin蛋白暘性錶達率。結果 NSCLC患者血清中Fascin暘性率(37．25%)明顯高于SCLC(7．69%)患者及肺部良性病變患者(5%)；在不同臨床分期的NSCLC患者中,Fascin暘性率差異有統計學意義。結論 Fascin在NSCLC患者中錶達提高,且與分期相關,有一定判斷預後的價值。
목적：탐토Fascin단백재폐암환자혈청중적표체급림상의의。방법검측61례폐암환자급20례폐부량성병변환자혈청중Fascin단백양성표체솔。결과 NSCLC환자혈청중Fascin양성솔(37．25%)명현고우SCLC(7．69%)환자급폐부량성병변환자(5%)；재불동림상분기적NSCLC환자중,Fascin양성솔차이유통계학의의。결론 Fascin재NSCLC환자중표체제고,차여분기상관,유일정판단예후적개치。
Objective To investigate the expression of serum Fascin in patients with lung cancer and its clini-cal significance. Methods The positive rate of Fascin expression was detected in 61 patients with lung cancer and 20 healthy controls by enzyme-linked immunosorbent assay. Results The positive rate of serum Fascin was 37. 25% in NSCLC patients, which was obviously higher than that in SCLC patients (7. 69%) and patients with benign lung lesions (5%) (P<0. 05), and it also had significant differences among NSCLC patients at different TNM stages. Conclusion It suggests that the expression of serum fascin is an effective indicator of tumor aggressiveness in NSCLC patients.
