CAJ | 학술논문

目的：分析小儿肺炎的痰培养致病菌种类分布以及耐药性状况。方法将我院收治的124例肺炎患儿在入院后收集痰液进行痰培养及致病菌分离，分析病原菌分布并实施常规药敏检测。结果124例患儿的痰标本总计培养出阳性致病菌87株，总阳性率为70．16%。其中革兰氏阴性菌62株，占71.26%，以大肠埃希氏菌居首位；革兰氏阳性菌21株，占24．14%，以金黄色葡萄球菌居首位；真菌4株，占4.60%。革兰氏阴性菌对青霉素类药物以及第一代、第二代头孢菌素类药物的耐药性较高。各类细菌对青霉素类的氨苄西林及阿莫西林的耐药性在40%以上，而对氨基糖苷类抗菌药物、喹诺酮类药物、头孢菌素类药物特别是第三代头孢菌素的耐药性不高。结论革兰氏阴性杆菌是目前小儿肺炎的主要致病菌，大多数致病菌对第三代头孢类抗菌药物敏感。
목적：분석소인폐염적담배양치병균충류분포이급내약성상황。방법장아원수치적124례폐염환인재입원후수집담액진행담배양급치병균분리，분석병원균분포병실시상규약민검측。결과124례환인적담표본총계배양출양성치병균87주，총양성솔위70．16%。기중혁란씨음성균62주，점71.26%，이대장애희씨균거수위；혁란씨양성균21주，점24．14%，이금황색포도구균거수위；진균4주，점4.60%。혁란씨음성균대청매소류약물이급제일대、제이대두포균소류약물적내약성교고。각류세균대청매소류적안변서림급아막서림적내약성재40%이상，이대안기당감류항균약물、규낙동류약물、두포균소류약물특별시제삼대두포균소적내약성불고。결론혁란씨음성간균시목전소인폐염적주요치병균，대다수치병균대제삼대두포류항균약물민감。
Objective To analyze the pathogen features and drug sensitivity test results of sputum culture in children with pneumonia. Methods 124 children with pneumonia were given sputum culture and pathogen isolation, then the pathogen features and drug sensitivity test results were analyzed. Results There were 87 strains of patho-gens isolated, and the total positive rate was 70. 16%, which included 62 strains of Gram-negative bacteria, 21 strains of Gram-positive bacteria and 4 strains of fungus. Gram-negative bacteria showed a high resistance to penicillin and the first and second generation cephalosporin. All bacteria showed at least 40% resistance to ampicillin and amoxicillin, and a low resistance to aminoglycoside antibiotics, quinolones, and the third generation cephalosporin. Conclusion Gram-negative bacteria is the main pathogen in children with pneumonia, and most pathogens are sensi-tive to the third generation cephalosporin.