CAJ | 학술논문

目的：探讨血清降钙素原在评估社区获得性肺炎( CAP)病情严重程度的临床价值。方法收集2011年1月~2012年12月在西丽人民医院接受治疗的CAP患者80例，分≥65岁组50例；<65岁组30例，评价两组患者血清降钙素原、C-反应蛋白、白细胞计数、CURB-65和肺炎严重程度指数( PSI )之间的相关性。结果血清降钙素原( PCT)与CURB-65、PSI在总体上具有正相关性。血清降钙素原和CURB-65在≥65岁组CAP中尤其具有显著的正相关(r=0．408)。C-反应蛋白或白细胞水平与CAP严重程度之间的相关性较低。结论血清降钙素原比C-反应蛋白、白细胞计数更有助于临床预测CAP的严重程度，尤其是对于年龄大于65岁的老年患者。
목적：탐토혈청강개소원재평고사구획득성폐염( CAP)병정엄중정도적림상개치。방법수집2011년1월~2012년12월재서려인민의원접수치료적CAP환자80례，분≥65세조50례；<65세조30례，평개량조환자혈청강개소원、C-반응단백、백세포계수、CURB-65화폐염엄중정도지수( PSI )지간적상관성。결과혈청강개소원( PCT)여CURB-65、PSI재총체상구유정상관성。혈청강개소원화CURB-65재≥65세조CAP중우기구유현저적정상관(r=0．408)。C-반응단백혹백세포수평여CAP엄중정도지간적상관성교저。결론혈청강개소원비C-반응단백、백세포계수경유조우림상예측CAP적엄중정도，우기시대우년령대우65세적노년환자。
Objective To evaluate the clinical value of procalcitonin as a predictor of severity in patients with community-acquired pneumonia ( CAP) . Methods 80 patients with CAP were divided into two groups (≥65 years, n=50; <65 years, n=30). Their procalcitonin, C-reactive protein (CRP), white blood cell, confusion, uremia, respiratory rate, blood pressure, CURB-65 and pneumonia severity of index ( PSI) were recorded. Results The level of procalcitonin was positively correlated with CURB-65 and PSI, which was especially stronger in the elderly group (r=0. 408). The correlation between the levels of CRP or WBC and CAP severity was low. Conclu-sion The level of procalcitonin is more useful than the levels of CRP or WBC to predict the severity of CAP.