中国麻风皮肤病杂志
中國痳風皮膚病雜誌
중국마풍피부병잡지
CHINA JOURNAL OF LEPROSY AND SKIN DISEASES
2014年
10期
586-589
,共4页
王思农%张博%柳文红%杨鹏斐
王思農%張博%柳文紅%楊鵬斐
왕사농%장박%류문홍%양붕비
生肌白玉膏%创面%EGF%VEGF
生肌白玉膏%創麵%EGF%VEGF
생기백옥고%창면%EGF%VEGF
Shengjibaiyu ointment%wounds%EGF%VEGF
目的::评价生肌白玉膏对大鼠深 II 度烫伤创面肉芽组织中表皮生长因子(EGF)和血管内皮生长因子(VEGF)的影响。方法:80只深 II 度烫伤大鼠随机分为生肌白玉膏组、美宝湿润烧伤组,生理盐水组和空白组,在第3、7、14、21天用免疫组化方法测定创面肉芽组织中 EGF、VEGF 阳性细胞变化。结果:实验组大鼠创面肉芽组织中 EGF 和 VEGF 阳性表达明显高于其他组(P<0.01)。结论:生肌白玉膏可能通过影响 EGF 和 VEGF 促进创面愈合。
目的::評價生肌白玉膏對大鼠深 II 度燙傷創麵肉芽組織中錶皮生長因子(EGF)和血管內皮生長因子(VEGF)的影響。方法:80隻深 II 度燙傷大鼠隨機分為生肌白玉膏組、美寶濕潤燒傷組,生理鹽水組和空白組,在第3、7、14、21天用免疫組化方法測定創麵肉芽組織中 EGF、VEGF 暘性細胞變化。結果:實驗組大鼠創麵肉芽組織中 EGF 和 VEGF 暘性錶達明顯高于其他組(P<0.01)。結論:生肌白玉膏可能通過影響 EGF 和 VEGF 促進創麵愈閤。
목적::평개생기백옥고대대서심 II 도탕상창면육아조직중표피생장인자(EGF)화혈관내피생장인자(VEGF)적영향。방법:80지심 II 도탕상대서수궤분위생기백옥고조、미보습윤소상조,생리염수조화공백조,재제3、7、14、21천용면역조화방법측정창면육아조직중 EGF、VEGF 양성세포변화。결과:실험조대서창면육아조직중 EGF 화 VEGF 양성표체명현고우기타조(P<0.01)。결론:생기백옥고가능통과영향 EGF 화 VEGF 촉진창면유합。
Objective: To evaluate the effects of Shengjibaiyu ointment on the expression of epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) in granulation tissue of deep II degree scald wounds in rats. Methods: Eighty rats were divided into Shengjibaiyu ointment group, MEBO group, sa-line group and blank group. EGF and VEGF were detected by immunohistochemical method at day 3, 7, 14, 21. Results: The expression of EGF and VEGF in experimental group was higher than those in other groups (P<0.01). Conclusion: Shengjibaiyu ointment may promote the scald wound healing by influencing EGF and VEGF.