CAJ | 학술논문

脂肪母细胞瘤(lipoblastoma)和脂肪母细胞瘤病(lipoblastomatosis)为少见的儿童软组织良性肿瘤。Jaffe于1924年首先使用。lipoblastoma描述为未成熟脂肪细胞的肿瘤。Vel ios等人于1958年使用lipoblastomatosis描述新生儿脂肪组织内良性新生物。其后陆续有个案报道，并总结出其生物学行为特征。肿瘤局限于局部者称脂肪母细胞瘤；病变弥漫且向周围组织或肌肉浸润者称脂肪母细胞瘤病(lipoblastomatosis)[1]。本文报道脂肪母细胞瘤2例，通过探讨其临床表现、组织学形态、免疫学表型以及鉴别诊断，进而促进对此种少见肿瘤的认识，避免误诊误治。
지방모세포류(lipoblastoma)화지방모세포류병(lipoblastomatosis)위소견적인동연조직량성종류。Jaffe우1924년수선사용。lipoblastoma묘술위미성숙지방세포적종류。Vel ios등인우1958년사용lipoblastomatosis묘술신생인지방조직내량성신생물。기후륙속유개안보도，병총결출기생물학행위특정。종류국한우국부자칭지방모세포류；병변미만차향주위조직혹기육침윤자칭지방모세포류병(lipoblastomatosis)[1]。본문보도지방모세포류2례，통과탐토기림상표현、조직학형태、면역학표형이급감별진단，진이촉진대차충소견종류적인식，피면오진오치。
Lipoblastoma and lipoblastomatosis is a rare kind of benign soft tissue tumors for children. Jaffe was the first to use in 1924. Lipoblastoma was described as solid tumors of immature fat cel s. Vel ios, etc. used it to define a newborn new creatures in the benign fatty tissues in 1958. More cases ware reported subsequently and sumed up its biological behavior characteristics. Tumor confined to localization cal lipoblastoma; and those infiltrating to the surrounding tissue cal lipoblastomatosis [1]. This paper reports 2 cases of lipoblastoma by exploring its clinical manifestations, histological morphology, immunophenotype and differential diagnosis, thus to promoting awareness of this rare tumor to avoid misdiagnosis.