中国处方药
中國處方藥
중국처방약
CHINA PRESCRIPTION DRUG
2014年
10期
10-11
,共2页
地佐辛%舒芬太尼%咳嗽
地佐辛%舒芬太尼%咳嗽
지좌신%서분태니%해수
Dizocine%Sulfentanil%Cough
目的：观察妇科全麻诱导前静脉注射地佐辛对舒芬太尼诱发咳嗽反射的影响。方法择期手术患者120例，随机均分为两组，分别于麻醉诱导前静脉注射地佐辛0.05 mg/kg（用生理盐水稀释至5 mL）（A组）或生理盐水5 mL（B组），5 min后于5 s内静脉注射舒芬太尼0.3μg/kg，观察1 min，记录咳嗽反射的发生率和强度。记录插管前后SBP、DBP和HR的变化。结果两组插管前后SBP、DBP和HR的比较差异无统计学意义。A组咳嗽反射的发生率、反射强度明显低于B组（8%vs.28%，P＜0.05）。结论预先静脉注射地佐辛0.05 mg/kg可以有效降低妇科全麻诱导舒芬太尼诱发咳嗽反射的发生率。
目的：觀察婦科全痳誘導前靜脈註射地佐辛對舒芬太尼誘髮咳嗽反射的影響。方法擇期手術患者120例，隨機均分為兩組，分彆于痳醉誘導前靜脈註射地佐辛0.05 mg/kg（用生理鹽水稀釋至5 mL）（A組）或生理鹽水5 mL（B組），5 min後于5 s內靜脈註射舒芬太尼0.3μg/kg，觀察1 min，記錄咳嗽反射的髮生率和彊度。記錄插管前後SBP、DBP和HR的變化。結果兩組插管前後SBP、DBP和HR的比較差異無統計學意義。A組咳嗽反射的髮生率、反射彊度明顯低于B組（8%vs.28%，P＜0.05）。結論預先靜脈註射地佐辛0.05 mg/kg可以有效降低婦科全痳誘導舒芬太尼誘髮咳嗽反射的髮生率。
목적：관찰부과전마유도전정맥주사지좌신대서분태니유발해수반사적영향。방법택기수술환자120례，수궤균분위량조，분별우마취유도전정맥주사지좌신0.05 mg/kg（용생리염수희석지5 mL）（A조）혹생리염수5 mL（B조），5 min후우5 s내정맥주사서분태니0.3μg/kg，관찰1 min，기록해수반사적발생솔화강도。기록삽관전후SBP、DBP화HR적변화。결과량조삽관전후SBP、DBP화HR적비교차이무통계학의의。A조해수반사적발생솔、반사강도명현저우B조（8%vs.28%，P＜0.05）。결론예선정맥주사지좌신0.05 mg/kg가이유효강저부과전마유도서분태니유발해수반사적발생솔。
Objective To evaluate the effects of intravenous dizocine on sulfentanil-induced cough during the induction of general anesthesia in gynecological.Methods One hundred and twenty ASA I orⅡpatients undergoing elective surgery were randomly derided into two groups with 60 cases in each group.Five minutes before sulfentanil bolus(3μg/kg)iv,patients received either dizocine(0.05 mg/kg diluted to 5 mL with normal saline;group A) or normal saline(5 mL;group B).Two minutes after intravenous injection of sulfentanil bolus,the frequency and intensity of coughing were observed. SBP, DBP,HR were recorded before and after intubation.Results The cough frequency was significantly lower in group A than that in group B(8%vs. 28%,P<0.05).Conclusion Premedication with intravenous dizocine 0.05 mg/kg may effectively reduce sulfentanil-induced cough during the induction of general anesthesia in gynecological..
