CAJ | 학술논문

目的：分析皮质下动脉硬化性脑病（SAE）患者血清hs-CRP测定的临床价值。方法SAE患者90例为观察组，同期健康志愿者90例作为对照组，对比两组血清hs-CRP水平；患者按病情程度分为轻、中、重，对比观察各组间hs-CRP水平。结果观察组平均血清hs-CRP水平显著高于对照组，不同程度病情间的hs-CRP水平亦有明显差异，程度越严重指标水平越高，差异均有统计学意义（P＜0.05）。结论SAE患者血清hs-CRP水平相比正常人明显升高，且随着病情发展程度而逐渐升高，与病情之间有着密切的关系。
목적：분석피질하동맥경화성뇌병（SAE）환자혈청hs-CRP측정적림상개치。방법SAE환자90례위관찰조，동기건강지원자90례작위대조조，대비량조혈청hs-CRP수평；환자안병정정도분위경、중、중，대비관찰각조간hs-CRP수평。결과관찰조평균혈청hs-CRP수평현저고우대조조，불동정도병정간적hs-CRP수평역유명현차이，정도월엄중지표수평월고，차이균유통계학의의（P＜0.05）。결론SAE환자혈청hs-CRP수평상비정상인명현승고，차수착병정발전정도이축점승고，여병정지간유착밀절적관계。
Objective To study sigificance of CRP level in patients with subcortical arteriosclerotic encephalopathy(SAE). Methods 90 SAE patients and 90 health cases were included. Patients were divided into three subgroups:mild group,moderate group and severe group. Hs-CRP level was compared among these three subgroups. Results The serum hs-CRP level in SAE group were higher than it in the control group(P<0.05). The significant difference were showed in different SAE subgroups(P < 0.05). Conclusion The serum level of hs-CRP was significantly higher in patients with SAE and was associated with disease severity .