CAJ | 학술논문

目的：比较不同位置心肌梗塞患者的血浆尿酸水平。方法以175例急性心肌梗死患者及42例非冠心病患者为研究对象，前者分为非ST段抬高型心肌梗塞、急性前间壁心肌梗塞、急性前壁心肌梗塞、急性广泛前壁心肌梗塞、急性下壁心肌梗塞、急性下壁、后壁和/或右室心肌梗塞。分别测各组的血清尿酸水平。结果尿酸水平在急性下壁心肌梗死患者（341.38±92.97umol/l）明显高于急性前间壁心梗（294.07±96.60 umol/l，P<0.05）、急性前壁心梗（268.44±89.75 umol/l，P<0.01）及急性广泛前壁心梗患者（262.28±96.30 umol/l，P<0.01）。结论尿酸对不同冠状动脉的促动脉粥样硬化作用程度可能因解剖位置不同而不同，其中以下壁为著，为筛选心梗后降低尿酸水平可能的获益人群的临床试验提供临床依据。
목적：비교불동위치심기경새환자적혈장뇨산수평。방법이175례급성심기경사환자급42례비관심병환자위연구대상，전자분위비ST단태고형심기경새、급성전간벽심기경새、급성전벽심기경새、급성엄범전벽심기경새、급성하벽심기경새、급성하벽、후벽화/혹우실심기경새。분별측각조적혈청뇨산수평。결과뇨산수평재급성하벽심기경사환자（341.38±92.97umol/l）명현고우급성전간벽심경（294.07±96.60 umol/l，P<0.05）、급성전벽심경（268.44±89.75 umol/l，P<0.01）급급성엄범전벽심경환자（262.28±96.30 umol/l，P<0.01）。결론뇨산대불동관상동맥적촉동맥죽양경화작용정도가능인해부위치불동이불동，기중이하벽위저，위사선심경후강저뇨산수평가능적획익인군적림상시험제공림상의거。
Objective:To study the expression of uric acid in different wals of acute myocardial infarction. Method The expression of serum uric acid in 175 acute myocardial infarction and 42 non-coronary artery disease was detected. The former one was grouped as Non-ST elevation myocardial infarction, prior anteroseptal ST elevation myocardial infarction (STEMI), anterior STEMI,extensive anterolateral STEMI, inferior STEMI, inferoposterior with or without right ventricle STEMI. Result The serum uric acid in inferior STEMI(341.38±92.97umol/l) was higher than prior anteroseptal STEMI(294.07±96.60 umol/l, P<0.05), anterior STEMI(268.44±89.75 umol/l, P<0.01) and extensive anterolateral STEMI(262.28±96.30 umol/l, P<0.01). Conclusion Uric acid may take different part in the atherosclerosis process in different kinds of coronary artery for the anatomy, the inferior wal maybe the serious one, in which we might be benefit from uric acid controling after myocardial infarction.