医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
10期
46-47
,共2页
香连丸药粉%钴60辐照%微生物检测%高效液相法
香連汍藥粉%鈷60輻照%微生物檢測%高效液相法
향련환약분%고60복조%미생물검측%고효액상법
Xianglianwan Powder%Co-60irradiation%Microbiological Tests%HPLC
目的：研究制定香连丸药粉在辐照前后的变化情况，利用钴60对其以不同剂量照射，并对药粉辐照前后的外观性状、微生物检测、含量测定等质量变化进行比较研究。方法观测药粉外观性状的变化，钴60辐射灭菌效果；采用高效液相法对木香进行含量测定。结果经过一定剂量辐照后药粉外观无明显变化、灭菌效果好、药粉有效成分无显著变化。结论该药粉在一定剂量范围内是可以利用辐照来灭菌的，其质量不会改变。
目的：研究製定香連汍藥粉在輻照前後的變化情況，利用鈷60對其以不同劑量照射，併對藥粉輻照前後的外觀性狀、微生物檢測、含量測定等質量變化進行比較研究。方法觀測藥粉外觀性狀的變化，鈷60輻射滅菌效果；採用高效液相法對木香進行含量測定。結果經過一定劑量輻照後藥粉外觀無明顯變化、滅菌效果好、藥粉有效成分無顯著變化。結論該藥粉在一定劑量範圍內是可以利用輻照來滅菌的，其質量不會改變。
목적：연구제정향련환약분재복조전후적변화정황，이용고60대기이불동제량조사，병대약분복조전후적외관성상、미생물검측、함량측정등질량변화진행비교연구。방법관측약분외관성상적변화，고60복사멸균효과；채용고효액상법대목향진행함량측정。결과경과일정제량복조후약분외관무명현변화、멸균효과호、약분유효성분무현저변화。결론해약분재일정제량범위내시가이이용복조래멸균적，기질량불회개변。
Objective In order to study and establish the changes of the Xianglianwan powder before and after irradiation ,we use Co-60 to irradiate with different dosage and comparative study on the quality changes of the External Properties, Microbiological Tests, Content Determination before and after irradiation. Method We observe changes of the External Properties and the Sterilization Effect of Co-60.We use the HPLC method to determinate the contention of the Radix Aucklandiae. Results We find no significant changes in powder ingredients and External Property after irradiation in a certain dosage, with a good Sterilization Effect. Conclusion The powder can be radio-sterilized in a certain dosage range, without changes in quality.
