CAJ | 학술논문

CXC 趋化因子配体10（CXCL10）也叫 IFN 诱导蛋白10，属于 CXC 趋化因子家族非ELR 亚族的小分子趋化因子，对白细胞转运及内皮与血管平滑肌等组织细胞功能有重要作用。它们通过与特异性 CXCR3受体结合调控系列炎症反应，在心血管疾病中有重要表现。该文的目的在于阐述 CXCL10在各类心血管疾病中的功能并讨论其在将来的心血管疾病研究模式中作为生物学标记的可能性。
CXC 추화인자배체10（CXCL10）야규 IFN 유도단백10，속우 CXC 추화인자가족비ELR 아족적소분자추화인자，대백세포전운급내피여혈관평활기등조직세포공능유중요작용。타문통과여특이성 CXCR3수체결합조공계렬염증반응，재심혈관질병중유중요표현。해문적목적재우천술 CXCL10재각류심혈관질병중적공능병토론기재장래적심혈관질병연구모식중작위생물학표기적가능성。
CXC chemokine ligand 1 0 (CXCL1 0),also known as interferon-inducible protein-1 0 (IP-1 0),is a small chemokine belonging to the non-ELR-CXC chemokine family,which plays a pivotal role in leu-kocyte trafficking and cellular and tissue functions,such as endothelial and vascular smooth muscle cells.CX-CL1 0 is able to regulate a cascade of inflammatory responses by binding to specific CXCR3 receptor,regarded as vital manifestations in cardiovascular diseases (CVD).The purpose of this review is to describe the func-tions of CXCL1 0 in different CVDs and discuss the possibility of utilizing CXCL1 0 as a potential biomarker in CVD study pattern.