陕西医学杂志
陝西醫學雜誌
협서의학잡지
SHAANXI MEDICAL JOURNAL
2014年
10期
1340-1341
,共2页
妊娠%异位/治疗%子宫动脉栓塞术/方法%甲氨蝶呤/治疗应用
妊娠%異位/治療%子宮動脈栓塞術/方法%甲氨蝶呤/治療應用
임신%이위/치료%자궁동맥전새술/방법%갑안접령/치료응용
Pregnancy%ectopic/therapy%Uterine artery embolization/methods%Methotrexate/thera-peutic use
目的：观察子宫动脉栓塞术联合局部甲氨蝶呤（MTX）化疗治疗宫颈妊娠的安全性及有效性。方法：40例宫颈妊娠患者给予子宫动脉栓塞及子宫动脉灌注MTX 50mg化疗，以30例给予局部肌注MTX 50mg的患者作为对照组。观察术后1周β-HCG水平变化及以及清宫术时的出血量。结果：观察组患者术前和术后血清β-HCG水平变化与对照组无明显差异（P＞0．05）；但清宫术中出血量平均为50±17ml ，显著低于对照组的300±70ml（P＜0．05）。结论：子宫动脉局部灌注和MTX肌注对于宫颈妊娠患者血清β-HCG的影响无差异，但子宫动脉栓塞术后患者的平均阴道出血量明显小于对照组患者，故子宫动脉栓塞术对于减少术后出血量具有重要作用。
目的：觀察子宮動脈栓塞術聯閤跼部甲氨蝶呤（MTX）化療治療宮頸妊娠的安全性及有效性。方法：40例宮頸妊娠患者給予子宮動脈栓塞及子宮動脈灌註MTX 50mg化療，以30例給予跼部肌註MTX 50mg的患者作為對照組。觀察術後1週β-HCG水平變化及以及清宮術時的齣血量。結果：觀察組患者術前和術後血清β-HCG水平變化與對照組無明顯差異（P＞0．05）；但清宮術中齣血量平均為50±17ml ，顯著低于對照組的300±70ml（P＜0．05）。結論：子宮動脈跼部灌註和MTX肌註對于宮頸妊娠患者血清β-HCG的影響無差異，但子宮動脈栓塞術後患者的平均陰道齣血量明顯小于對照組患者，故子宮動脈栓塞術對于減少術後齣血量具有重要作用。
목적：관찰자궁동맥전새술연합국부갑안접령（MTX）화료치료궁경임신적안전성급유효성。방법：40례궁경임신환자급여자궁동맥전새급자궁동맥관주MTX 50mg화료，이30례급여국부기주MTX 50mg적환자작위대조조。관찰술후1주β-HCG수평변화급이급청궁술시적출혈량。결과：관찰조환자술전화술후혈청β-HCG수평변화여대조조무명현차이（P＞0．05）；단청궁술중출혈량평균위50±17ml ，현저저우대조조적300±70ml（P＜0．05）。결론：자궁동맥국부관주화MTX기주대우궁경임신환자혈청β-HCG적영향무차이，단자궁동맥전새술후환자적평균음도출혈량명현소우대조조환자，고자궁동맥전새술대우감소술후출혈량구유중요작용。
Objective:To study the effect of methotrexate chemotherapy and uterine artery embolization in the treatment of cervical pregnancy .Methods :40 patients were received embolization of bilateral uterine arteries in combination with intra-arterial methotrexate(MTX) injection ,30 patients in control group were cured with intramus-cular methotrexate injection .After the treatment ,the vaginal bleeding was measured in curettage surgery and the re-duction of serum beta-human chorionic gonadotropin (β-HCG ) was evaluated .Results :There was no statistical differences in the change of β-HCG Between groups .However ,in observation group the amount of vaginal bleeding significantly reduced in curettage surgery .Conclusion:Uterine artery embolization is a safe and effective treatment for cervical pregnancy .
