粮食与油脂
糧食與油脂
양식여유지
CEREALS & OILS
2014年
10期
50-52
,共3页
大豆磷脂软胶囊保健食品%化学性肝损伤%动物实验
大豆燐脂軟膠囊保健食品%化學性肝損傷%動物實驗
대두린지연효낭보건식품%화학성간손상%동물실험
softcapsulehealth food made from soybean phospholipid%chemical liver injuny%animal experiments
以大豆磷脂为功效成分制备的软胶囊保健食品为受试物，研究其对小鼠化学性肝损伤的辅助保护作用。实验动物为健康雄性成年KM小鼠，每只体重18~22 g，将30只小鼠随机分成3组。以四氯化碳致小鼠化学性肝损伤为模型，对小鼠进行灌胃大豆磷脂软胶囊保健食品。测定第30天四氯化碳损伤后血清中谷丙转氨酶（ALT）和谷草转氨酶（AST）活性。结果显示，模型对照组小鼠血清中ALT和AST活性很高，而受试物组小鼠血清中ALT（141.74±21.33 U/L）和AST （127.53±8.54 U/L）活性明显低于模型组小鼠（ρ＜0.01）。研究结果表明，以大豆磷脂为功效成分制备的软胶囊保健食品对化学性肝损伤具有显著的保护作用。
以大豆燐脂為功效成分製備的軟膠囊保健食品為受試物，研究其對小鼠化學性肝損傷的輔助保護作用。實驗動物為健康雄性成年KM小鼠，每隻體重18~22 g，將30隻小鼠隨機分成3組。以四氯化碳緻小鼠化學性肝損傷為模型，對小鼠進行灌胃大豆燐脂軟膠囊保健食品。測定第30天四氯化碳損傷後血清中穀丙轉氨酶（ALT）和穀草轉氨酶（AST）活性。結果顯示，模型對照組小鼠血清中ALT和AST活性很高，而受試物組小鼠血清中ALT（141.74±21.33 U/L）和AST （127.53±8.54 U/L）活性明顯低于模型組小鼠（ρ＜0.01）。研究結果錶明，以大豆燐脂為功效成分製備的軟膠囊保健食品對化學性肝損傷具有顯著的保護作用。
이대두린지위공효성분제비적연효낭보건식품위수시물，연구기대소서화학성간손상적보조보호작용。실험동물위건강웅성성년KM소서，매지체중18~22 g，장30지소서수궤분성3조。이사록화탄치소서화학성간손상위모형，대소서진행관위대두린지연효낭보건식품。측정제30천사록화탄손상후혈청중곡병전안매（ALT）화곡초전안매（AST）활성。결과현시，모형대조조소서혈청중ALT화AST활성흔고，이수시물조소서혈청중ALT（141.74±21.33 U/L）화AST （127.53±8.54 U/L）활성명현저우모형조소서（ρ＜0.01）。연구결과표명，이대두린지위공효성분제비적연효낭보건식품대화학성간손상구유현저적보호작용。
With softcapsulehealth food made from soybean phospholipid as materials,to study its protection functiononchemicalhepatic injury in mice.Healthy kunming male mice,weighting 18~22 g, the 30 mice were randomized into 3 groups,model establishmentofchemicalhepatic injury in mice withcarbon tettrachloride inducedhepatotoxicity.The mice were gavaged softcapsulehealth food made from soybean phospholipid 30 days. In thirtieth days,aminotransferase(ALT) and aspartate aminotransferase(AST) activities in serum were determined aftercarbon tetrachloride-injury.The results showed thatAST andALT were veryhigh in serumof the modelcontrol group,butALT (141.74±21.33 U/L) andAST(127.53±8.54 U/L) activities in serum after gavaged softcapsule health food made from soybean phospholipid group wasobviously lower than model group(ρ<0.01). It is proved that softcapsulehealth food made from soybean phospholipidhas auxiliary protection functiononchemical liver injury.
