CAJ | 학술논문

目的探讨对于急性ST段抬高型心梗（STEMI）患者，早期应用rh-BNP（重组人脑利钠肽）对患者支架植入术后冠脉血流及近期预后的影响。方法入选沈阳医学院附属第二医院2013年3月~2014年3月急性STEMI并行PCI治疗的患者100例，其中，男性59例，女性41例，平均年龄(57.8±7.1)岁，随机分组（rh-BNP早期应用组,即试验组n=50例）与（常规组，即对照组，n=50例）的临床资料进行分析。结果试验组与对照组相比，PCI术中无复流及慢血流的发生率明显低于对照组，（<0.05）；住院期间的主要心血管事件发生率试验组明显低于对照组，（<0.05）。结论对于急性STEMI患者，尽早应用rh-BNP（重组人脑利钠肽）可以明显降低PCI术中无复流及慢血流的发生率，明显降低（MACE）的发生率。
목적탐토대우급성ST단태고형심경（STEMI）환자，조기응용rh-BNP（중조인뇌리납태）대환자지가식입술후관맥혈류급근기예후적영향。방법입선침양의학원부속제이의원2013년3월~2014년3월급성STEMI병행PCI치료적환자100례，기중，남성59례，녀성41례，평균년령(57.8±7.1)세，수궤분조（rh-BNP조기응용조,즉시험조n=50례）여（상규조，즉대조조，n=50례）적림상자료진행분석。결과시험조여대조조상비，PCI술중무복류급만혈류적발생솔명현저우대조조，（<0.05）；주원기간적주요심혈관사건발생솔시험조명현저우대조조，（<0.05）。결론대우급성STEMI환자，진조응용rh-BNP（중조인뇌리납태）가이명현강저PCI술중무복류급만혈류적발생솔，명현강저（MACE）적발생솔。
Objective To study intracoronary flow influence of early use of Lyophilized Recombinant Human Brain Natriuretic Peptide (rh-BNP) in patients with STEMI after intracoronary stenting use and short-term out comes. Methods One hundred STEMI patients (59 males,41 females,mean age 57.8±7.1 years old) admit ed during March,2013 to March 2014 were include in the study from shenzhou Hospital of Shenyang Medical Col ege. The patients were divided into the early use rh-BNP group (n=50) and the conventional medical treatment group (n=50). Clinical data analysis.Results The incidence of slow-flow and no-reflow of the early use rh-BNP group was lower than that of the conventional medical treatment group ( <0.05);the rate of MACE was al lower than that of common use rh-BNP group( <0.05). Conclusion Early use of Lyophilized Recombinant Human Brain Natriuretic Peptide (rh-BNP) patient with STEMI is feasible and can reduce not only the rate of no-reflow, but also slow flow and MACE during operation.