CAJ | 학술논문

目的：探讨血必净在产科高凝状态中的临床预防治疗效果。方法选择2011年6月~2013年6月住院的72例重度子痫前期患者作为研究对象，系统随机化法将其分为两组，对照组（36例）术后静脉滴注葛根素治疗，观察组（36例）术后静脉滴注血必净治疗，比较两组生产前后的凝血指标。结果观察组产后纤维蛋白原和血细胞积压两个指标值均明显下降（P＜0.05），D-二聚体指标平均值上升，但差异无统计学意义（P＞0.05）；对照组产前、产后血细胞积压、纤维蛋白原及D-二聚体3项标准均未见明显差异（P＞0.05）。结论血必净在预防治疗重度子痫前期高凝状态的临床效果显著，值得临床借鉴推广。
목적：탐토혈필정재산과고응상태중적림상예방치료효과。방법선택2011년6월~2013년6월주원적72례중도자간전기환자작위연구대상，계통수궤화법장기분위량조，대조조（36례）술후정맥적주갈근소치료，관찰조（36례）술후정맥적주혈필정치료，비교량조생산전후적응혈지표。결과관찰조산후섬유단백원화혈세포적압량개지표치균명현하강（P＜0.05），D-이취체지표평균치상승，단차이무통계학의의（P＞0.05）；대조조산전、산후혈세포적압、섬유단백원급D-이취체3항표준균미견명현차이（P＞0.05）。결론혈필정재예방치료중도자간전기고응상태적림상효과현저，치득림상차감추엄。
Objective To investigate clinical preventive effect of Xuebijing in the treatment of obstetric hypercoagulable state. Methods 72 cases of patients with severe preeclampsia were selected as research object, who accessed in our hospital from June 2011 to June 2013.The patients were divided into 2 groups, according to system randomization method. Puerarin was taken by the control group(36 cases) with intravenous infusion. Xuebijing was taken by the observation group(36 cases) with intravenous infusion. Coagulation parameters of both groups were then observed and compared. Results Postnatal fibrinogen and blood cells backlog of observation group significantly decreased(P < 0.05). D-dimer average value increased, but p value exceeded 0.05, so there was no statistical difference. Blood cells backlog, fibrinogen and D-dimer of control group in prenatal and postnatal had no significant difference(P > 0.05). Conclusion Xuebijing has a significant clinical preventive effect in the treatment of severe preeclampsia hypercoagulable state, which is worthy of clinical promotion.