CAJ | 학술논문

　　目的探讨胰岛素泵治疗妊娠糖尿病的临床疗效及安全性。方法选择2008年2月至2011年2月160例妊娠糖尿病围术期患者，随机分入对照组与观察组，每组各80例。对照组多次皮下胰岛素注射治疗，观察组胰岛素泵持续皮下输注，比较两组干预前后血糖水平、血糖达标时间、低血糖及母婴并发症发生率。结果两组治疗后血糖水平均明显下降（P＜0．01），但观察组血糖优于对照组（P＜0．05）；观察组血糖达标时间少于对照组（P＜0．05）；观察组低血糖发生率低于对照组（5．0％＜12．5％，P＜0．05），观察组母婴并发症发生率少于对照组，差异具有统计学意义（P＜0．05）。结论妊娠糖尿病患者使用胰岛素泵降糖达标时间快，血糖平稳，且安全性高。
　　목적탐토이도소빙치료임신당뇨병적림상료효급안전성。방법선택2008년2월지2011년2월160례임신당뇨병위술기환자，수궤분입대조조여관찰조，매조각80례。대조조다차피하이도소주사치료，관찰조이도소빙지속피하수주，비교량조간예전후혈당수평、혈당체표시간、저혈당급모영병발증발생솔。결과량조치료후혈당수평균명현하강（P＜0．01），단관찰조혈당우우대조조（P＜0．05）；관찰조혈당체표시간소우대조조（P＜0．05）；관찰조저혈당발생솔저우대조조（5．0％＜12．5％，P＜0．05），관찰조모영병발증발생솔소우대조조，차이구유통계학의의（P＜0．05）。결론임신당뇨병환자사용이도소빙강당체표시간쾌，혈당평은，차안전성고。
Objective To explore the clinical effect and safety of insulin pump treatment in gestational diabetes mellitus .Methods 160 cases with gestational diabetes mellitus were randomly divided into control group and obser-vation group ,80 patients for each group .Observation group was given continuous subcutaneous insulin injection by insulin pump and control group received multiple subcutaneous insulin injection .Blood glucose level ,time of reaching target of glucose control ,incidence of hypoglycemia and maternal and neonatal complications were compared between two groups .Results Blood glucose level greatly decreased after treatment in two groups (P< 0 .01) ,but level of blood glucose control in observation group was superior to control group (P<0 .05) .Time of reaching target of glu-cose control in observation group was less than that in control group (P<0 .05) .Incidence of hypoglycemia in obser-vation group was much lower than that in control group (5 .0% vs 12 .5% ,P<0 .05) .Incidence of maternal and neo-natal complications in observation group was much lower than that in control group (P<0 .05) .Conclusion Insulin pump treatment for gestational diabetes mellitus could acquire optimal glucose level rapidly and stably with high safe-ty .