CAJ | 학술논문

　　目的分析不同年龄和性别人群糖化血红蛋白（HbA1c）和空腹血糖（GLU ）之间的差异及其关系，探讨其在糖尿病防治中的意义。方法随机选取体检人群样本300例，其中35～55岁男性100例，55岁以上男性40例；35～55岁女性110例，55岁以上女性50例。静脉抽血分别检测糖化血红蛋白和空腹血糖，采用 t检验评估各组差异，并对二者进行直线回归分析。结果55岁以上人群，不论男女，其HbA1c和GLU与全部样本的差异存在统计学意义（P＜0．01）。35～55岁男性 HbA1c与GLU的相关性（r＝0．743）低于其他3组，与55岁以上男性组（ r＝0．961）和55岁以上女性组（ r＝0．896）差异有统计学意义（ P＜0．01），与35～55岁女性组（ r＝0．908）差异无统计学意义（P＞0．05）。结论 HbA1c可作为糖尿病病情监测和评估指标，对不同年龄人群应结合多因素综合判断疾病的发生发展趋势，尤其要做好对中青年人群的糖尿病预防工作。
　　목적분석불동년령화성별인군당화혈홍단백（HbA1c）화공복혈당（GLU ）지간적차이급기관계，탐토기재당뇨병방치중적의의。방법수궤선취체검인군양본300례，기중35～55세남성100례，55세이상남성40례；35～55세녀성110례，55세이상녀성50례。정맥추혈분별검측당화혈홍단백화공복혈당，채용 t검험평고각조차이，병대이자진행직선회귀분석。결과55세이상인군，불론남녀，기HbA1c화GLU여전부양본적차이존재통계학의의（P＜0．01）。35～55세남성 HbA1c여GLU적상관성（r＝0．743）저우기타3조，여55세이상남성조（ r＝0．961）화55세이상녀성조（ r＝0．896）차이유통계학의의（ P＜0．01），여35～55세녀성조（ r＝0．908）차이무통계학의의（P＞0．05）。결론 HbA1c가작위당뇨병병정감측화평고지표，대불동년령인군응결합다인소종합판단질병적발생발전추세，우기요주호대중청년인군적당뇨병예방공작。
Objective To analyze the differences of glycated hemoglobin (HbA1c) and fasting blood glucose (GLU) and their correlations in different ages and genders ,and to explore their significances in diabetes prevention and treatment .Methods Medical population sample of 300 cases were randomly selected ,including 100 cases of 35 to 55 years old males ,40 cases of over 55 years old males ,110 cases of 35 to 55 years old females and 50 cases of over 55 years old females .Venous bloods were measured for HbA 1c and GLU .T-test and linear regression analysis were per-formed .Results Over 55 years old ,regardless of gender ,there was significant difference (P<0 .01) in the values of HbA1c and GLU between old people groups and all other groups .Correlations of HbA1c and GLU in 35-55 years old males (r=0 .743) was lower than the other three groups ,with significant difference (P<0 .01) ,compared with over 55 years old males (r=0 .961) and females (r=0 .896) ,and without statistical difference (P>0 .05) ,compared with 35-55 years old females .Conclusion HbA1c could be used as monitoring and evaluation indicators of diabetes . To determine occurrence and development of diabetes in population at different ages ,multiple factors should be con-sidered .Prevention of diabetes in middle aged and young subject should be particularly paid more attention .