CAJ | 학술논문

目的：分析研究重度有机磷中毒伴呼吸衰竭患者的急救方法，分析解磷定对患者的治疗价值。方法选择2010年7月-2013年6月该院重度有机磷中毒伴呼吸衰竭的患者58例为研究对象，随机分为两组。对照组使用一般治疗方法，实验组使用解磷定治疗，对比观察两组治疗后的效果。结果实验组患者带机时间短，气管切开率低，患者3d内脱机率高，两组对比差异有统计学意义（P＜0.05）；实验组病死率低于对照组患者（P＜0.05）。结论对重症有机磷中毒伴呼吸衰竭患者给予解磷定急救治疗可以提高救治效果，患者撤机快，呼吸衰竭时间缩短，值得应用。
목적：분석연구중도유궤린중독반호흡쇠갈환자적급구방법，분석해린정대환자적치료개치。방법선택2010년7월-2013년6월해원중도유궤린중독반호흡쇠갈적환자58례위연구대상，수궤분위량조。대조조사용일반치료방법，실험조사용해린정치료，대비관찰량조치료후적효과。결과실험조환자대궤시간단，기관절개솔저，환자3d내탈궤솔고，량조대비차이유통계학의의（P＜0.05）；실험조병사솔저우대조조환자（P＜0.05）。결론대중증유궤린중독반호흡쇠갈환자급여해린정급구치료가이제고구치효과，환자철궤쾌，호흡쇠갈시간축단，치득응용。
Objective To analyze the first-aid method for patients with severe organophosphate poisoning and respiratory failure, and the ther-apeutic value of pralidoxime for the patients. Methods 58 cases of patients with severe organophosphate poisoning and respiratory failure admitted in our hospital from July, 2010 to June, 2013 were selected as the subjects, and they were randomly divided into two groups. The control group was treated with the general treatment method, and the experimental group was treated with prali-doxime. The treatment effect of two groups was observed and compared. Results The patients in the experimental group had short-er time with a ventilator, lower rate of tracheotomy, higher withdrawal probability of ventilator within 3d, the differences between two groups were statistically significant (P<0.05); the mortality of the experimental group was lower than that of the control group (P<0.05). Conclusion Pralidoxime given to the patients with severe organophosphate poisoning and respiratory failure for first-aid treatment can improve the treatment effect; patients need shorter time of needing for ventilation with shorter respiratory failure time, which is worthy of application.