重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2013年
23期
2728-2729,2732
,共3页
纳米炭%淋巴结%直肠癌
納米炭%淋巴結%直腸癌
납미탄%림파결%직장암
carbon nano-particle%lymph node%rectal cancer
目的探讨纳米炭示踪剂在中低位直肠癌根治术中的临床应用及效果。方法选择26例中低位直肠癌患者，分为纳米炭示踪剂注射组和常规组，纳米炭示踪剂注射组术前20～14 h注射，根据T M E原则行腹腔镜下根治术，术后分析比较两组检获淋巴结情况。结果注射组检获淋巴结总数287枚，高于常规组124枚（ P＜0．05）；平均淋巴结检获数（22．12±3．50）枚/例，高于常规组（9．56±1．50）枚/例（ P＜0．05）；平均小于5 m m淋巴结检获数（9．18±1．41）枚/例，高于常规组（3．50±0．82）枚/例（ P＜0．05）；平均阳性淋巴结阳性检获数（3．10±0．37）枚/例，与常规组（2．62±0．25）枚/例比较差异无统计学意义（ P＞0．05）。结论纳米炭示踪剂应用于中低位直肠癌根治术能提高淋巴结检获数，从而更准确地反映患者的淋巴结转移情况，能为术后临床分期、后期治疗提供帮助；能为术中清除淋巴结以及肿瘤远端切除提供指导。
目的探討納米炭示蹤劑在中低位直腸癌根治術中的臨床應用及效果。方法選擇26例中低位直腸癌患者，分為納米炭示蹤劑註射組和常規組，納米炭示蹤劑註射組術前20～14 h註射，根據T M E原則行腹腔鏡下根治術，術後分析比較兩組檢穫淋巴結情況。結果註射組檢穫淋巴結總數287枚，高于常規組124枚（ P＜0．05）；平均淋巴結檢穫數（22．12±3．50）枚/例，高于常規組（9．56±1．50）枚/例（ P＜0．05）；平均小于5 m m淋巴結檢穫數（9．18±1．41）枚/例，高于常規組（3．50±0．82）枚/例（ P＜0．05）；平均暘性淋巴結暘性檢穫數（3．10±0．37）枚/例，與常規組（2．62±0．25）枚/例比較差異無統計學意義（ P＞0．05）。結論納米炭示蹤劑應用于中低位直腸癌根治術能提高淋巴結檢穫數，從而更準確地反映患者的淋巴結轉移情況，能為術後臨床分期、後期治療提供幫助；能為術中清除淋巴結以及腫瘤遠耑切除提供指導。
목적탐토납미탄시종제재중저위직장암근치술중적림상응용급효과。방법선택26례중저위직장암환자，분위납미탄시종제주사조화상규조，납미탄시종제주사조술전20～14 h주사，근거T M E원칙행복강경하근치술，술후분석비교량조검획림파결정황。결과주사조검획림파결총수287매，고우상규조124매（ P＜0．05）；평균림파결검획수（22．12±3．50）매/례，고우상규조（9．56±1．50）매/례（ P＜0．05）；평균소우5 m m림파결검획수（9．18±1．41）매/례，고우상규조（3．50±0．82）매/례（ P＜0．05）；평균양성림파결양성검획수（3．10±0．37）매/례，여상규조（2．62±0．25）매/례비교차이무통계학의의（ P＞0．05）。결론납미탄시종제응용우중저위직장암근치술능제고림파결검획수，종이경준학지반영환자적림파결전이정황，능위술후림상분기、후기치료제공방조；능위술중청제림파결이급종류원단절제제공지도。
Objective To investigate the clinical application and curative effect of Carbon Nano-particles in curative resection of mid-low rectal cancer .Methods 26 patients with mid-low rectal cancer were divided equally into carbon nano-particle group and routine group .The labeling group were injected with carbon nano-particles 20~24 hours before operation and treated with TME laparoscopic radical resection .The data of lymph nodes detected in the two groups were compared .Results (1)Total number of lymph nodes detected in the labeling group was higher than that of the routine group (287 vs .124 ,P<0 .05) .(2)The labeling group had higher average lymph nodes detected per patient (22 .12 ± 3 .50 vs .9 .56 ± 1 .50 ,P< 0 .05) ,as well as higher average lymph nodes smaller than 5mm per patient(9 .18 ± 1 .41 vs .3 .50 ± 0 .82 ,P<0 .05) .(3)The metastasis rate of lymph nodes detected in la-beling group lacked statistical significance as compared with that of the routine group (3 .10 ± 0 .37 vs .2 .62 ± 0 .25 ,P>0 .05) .Con-clusion Adoption of carbon nano-particle in curative resection of rectal cancer can increase the number of lymph nodes detected ,re-veal more accurately the metastasis situation of lymph nodes ,facilitate the resection of lymph nodes and rectal cancer during the op-eration ,and provide guidance for postoperative clinical staging and treatment .
