中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2013年
24期
22-23
,共2页
孕酮%异位妊娠
孕酮%異位妊娠
잉동%이위임신
Progesterone%Ectopic pregnancy
目的：探讨孕酮检测在异位妊娠保守治疗中的价值。方法：异位妊娠患者50例，采用甲氨蝶蛉(MTX)单次肌肉注射，按照保守治疗成功与否分为成功组(34例)及失败组(16例)，患者在治疗前、治疗后均采用化学发光法检查β-hCG及孕酮，并对所测结果进行比较分析。结果：成功组孕酮值为(20.13±1.56)nmol/L，而失败组相应值为(40.17±0.97)nmol/L，两者比较差异有统计学意义(t=45.86，P<0.01)；在治疗成功组中血清β-hCG下降至标准的5 mIU/ml以下的时间是(23.00±2.01)d，血清孕酮下降至5 nmol/L时间为(13.81±1.30)d，两者比较差异有统计学意(t=15.84，P<0.001)；在治疗成功组中血清β-hCG开始下降距第一次给药时间是(8.05±1.23)d，血清孕酮开始下降距第一次给药时间是(4.54±0.64)d，两者比较差异有统计学意义(t=10.48，P<0.05)。结论：异位妊娠保守治疗成功的患者中血清孕酮降低所需时间较血清β-hCG短，对治疗结局更有预测意义。
目的：探討孕酮檢測在異位妊娠保守治療中的價值。方法：異位妊娠患者50例，採用甲氨蝶蛉(MTX)單次肌肉註射，按照保守治療成功與否分為成功組(34例)及失敗組(16例)，患者在治療前、治療後均採用化學髮光法檢查β-hCG及孕酮，併對所測結果進行比較分析。結果：成功組孕酮值為(20.13±1.56)nmol/L，而失敗組相應值為(40.17±0.97)nmol/L，兩者比較差異有統計學意義(t=45.86，P<0.01)；在治療成功組中血清β-hCG下降至標準的5 mIU/ml以下的時間是(23.00±2.01)d，血清孕酮下降至5 nmol/L時間為(13.81±1.30)d，兩者比較差異有統計學意(t=15.84，P<0.001)；在治療成功組中血清β-hCG開始下降距第一次給藥時間是(8.05±1.23)d，血清孕酮開始下降距第一次給藥時間是(4.54±0.64)d，兩者比較差異有統計學意義(t=10.48，P<0.05)。結論：異位妊娠保守治療成功的患者中血清孕酮降低所需時間較血清β-hCG短，對治療結跼更有預測意義。
목적：탐토잉동검측재이위임신보수치료중적개치。방법：이위임신환자50례，채용갑안접령(MTX)단차기육주사，안조보수치료성공여부분위성공조(34례)급실패조(16례)，환자재치료전、치료후균채용화학발광법검사β-hCG급잉동，병대소측결과진행비교분석。결과：성공조잉동치위(20.13±1.56)nmol/L，이실패조상응치위(40.17±0.97)nmol/L，량자비교차이유통계학의의(t=45.86，P<0.01)；재치료성공조중혈청β-hCG하강지표준적5 mIU/ml이하적시간시(23.00±2.01)d，혈청잉동하강지5 nmol/L시간위(13.81±1.30)d，량자비교차이유통계학의(t=15.84，P<0.001)；재치료성공조중혈청β-hCG개시하강거제일차급약시간시(8.05±1.23)d，혈청잉동개시하강거제일차급약시간시(4.54±0.64)d，량자비교차이유통계학의의(t=10.48，P<0.05)。결론：이위임신보수치료성공적환자중혈청잉동강저소수시간교혈청β-hCG단，대치료결국경유예측의의。
Objective:To discuss the value of the detecting serum level of progesterone for expectant treatment of ectopic pregnancy.Method:50 patients suffered from ectopic pregnancy were treated by MTX(intramuscular injection),34 patients succeeded (successful group) and 16 patient failed (failure group),the serum level of progesterone andβ-hCG were detected by chemiluminometry and compared between two groups by t-test.Result:The level of progesterone in successful group was (20.13±1.56)nmol/L,failure group was (40.17±0.97)nmol/L,the level of progesterone in successful group was lower than failure group, there was statistical difference between the two groups(t=45.86,P<0.01).The time thatβ-hCG descend to 5 mIU/ml was (23.00±2.01)days,progesterone descend to 5 nmol/L was(13.81±1.30)days in successful group,the latter was shorter than the former,there was statistical difference between the two groups(t=15.84, P<0.01).The time thatβ-hCG begin to descend from beginning was (8.05±1.23)days,the time that progesterone begin to descend from beginning was(4.54±0.64) days,the latter was shorter than the former ,there was statistical difference between the two groups(t=10.48,P<0.05).Conclusions:The time that progesterone begin to descend is shorter thanβ-hCG in expectant treatment of ectopic pregnancy,it plays an important role in predicating the result of ectopic pregnancy.
