CAJ | 학술논문

目的：探讨血氨检测在急性肝性脑病患者的应用价值。方法选取65例急性肝性脑病患者（观察组）与70例非肝性脑病患者（对照组），全部进行血氨、肝功能指标（AST、ALT、TP）的检查。结果观察组患者平均血氨水平（65.24±10.21）μmol/L，显著高于对照组（25.04±8.54）μmol/L，差异有统计学意义（P＜0.05）；而2组肝功能指标AST、ALT、TP水平[(52.36±10.21)U/L、(42.65±11.28)U/L、(68.77±11.31)g/L VS (31.24±10.37)U/L、(30.17±10.67)U/L、(72.54±6.41)g/L]比较差异无统计学意义；血氨诊断急性肝性脑病的ROC曲线下面积为0.904，当血氨为50μmol/L，灵敏度为0.68，特异度为97.6，阴性预测值为0.83，阳性预测值为0.93。结论血氨是急性肝性脑病诊断的较好指标，具有良好的特异性。
목적：탐토혈안검측재급성간성뇌병환자적응용개치。방법선취65례급성간성뇌병환자（관찰조）여70례비간성뇌병환자（대조조），전부진행혈안、간공능지표（AST、ALT、TP）적검사。결과관찰조환자평균혈안수평（65.24±10.21）μmol/L，현저고우대조조（25.04±8.54）μmol/L，차이유통계학의의（P＜0.05）；이2조간공능지표AST、ALT、TP수평[(52.36±10.21)U/L、(42.65±11.28)U/L、(68.77±11.31)g/L VS (31.24±10.37)U/L、(30.17±10.67)U/L、(72.54±6.41)g/L]비교차이무통계학의의；혈안진단급성간성뇌병적ROC곡선하면적위0.904，당혈안위50μmol/L，령민도위0.68，특이도위97.6，음성예측치위0.83，양성예측치위0.93。결론혈안시급성간성뇌병진단적교호지표，구유량호적특이성。
Objective To discuss the application value of blood ammonia in patients with acute hepatic encephalopathy. Methods Choose 65 cases of patients with acute hepatic encephalopathy (observation group) and 70 cases of patients with no hepatic encephalopathy (control group), all patients were checked blood ammonia, liver function index (AST, ALT and TP). Results The average blood ammonia levels of observation group is (65.24±10.21)μmol/L, significantly lower than control group (25.04±8.54) umol/L, statistically significant difference (P<0.05), and two groups of liver function index level of AST, ALT and TP [(52.36±10.21) U/L, (42.65±11.28) U/L, (68.77±11.31) g/L VS (31.24±10.37) U/L, (30.17±10.67) U/L, (72.54±6.41) g/L] there was no significant difference compared;Blood ammonia in the diagnosis of acute hepatic encephalopathy area under the ROC curve is 0.904, when the blood ammonia in 50μmol/L, the sensitivity of 0.68, a specific degree of 97.6, negative predictive value of 0.83, the positive predictive value of 0.93. Conclusion Blood ammonia is a good index of the diagnosis of acute hepatic encephalopathy, it has the good specificity.