CAJ | 학술논문

中毒性表皮坏死松解症(TEN)是一种急性皮肤炎症反应,属于重型药疹的一类.随着抗生素、非甾体类解热镇痛等药物在救治危重患者中的广泛应用,TEN在临床上,特别是ICU病房中其发病率有增高趋势.TEN病死率较高,且对危重患者的整体预后有较大影响.本文报道南京军区南京总医院普通外科收治的1例重症急性胰腺炎患者,应用阿司匹林预防血栓及栓塞并发症过程中并发TEN,总结该病的诊断和治疗经验以供临床医师参考.
중독성표피배사송해증(TEN)시일충급성피부염증반응,속우중형약진적일류.수착항생소、비치체류해열진통등약물재구치위중환자중적엄범응용,TEN재림상상,특별시ICU병방중기발병솔유증고추세.TEN병사솔교고,차대위중환자적정체예후유교대영향.본문보도남경군구남경총의원보통외과수치적1례중증급성이선염환자,응용아사필림예방혈전급전새병발증과정중병발TEN,총결해병적진단화치료경험이공림상의사삼고.
Toxic epidermal necrolysis (TEN) is an acute skin inflammation,which belongs to heavy drug eruption.With the extensive and widespread use of antibiotics,nonsteroidal antipyretic analgesics and other pharmacotherapies in the treatment of critically ill patients,the trend of morbidity of TEN is gradually increased,especially in intensive care unit.In consideration of the high mortality rate of TEN and its great influence on the overall prognosis of patients with critical illness,we summarized the diagnosis and treatment experiences in the management of TEN based on retrospective analysis of one patient with severe acute pancreatitis and TEN.