中成药
中成藥
중성약
CHINESE TRADITIONAL PATENT MEDICINE
2014年
5期
1000-1004
,共5页
邱丘%吴霞%李国强%李药兰%王国才
邱丘%吳霞%李國彊%李藥蘭%王國纔
구구%오하%리국강%리약란%왕국재
蟛蜞菊%菊科%化学成分
蟛蜞菊%菊科%化學成分
팽기국%국과%화학성분
目的 研究菊科蟛蜞菊属植物蟛蜞菊的化学成分.方法 蟛蜞菊全草粉碎后用95％乙醇提取,提取物分别经过石油醚、乙酸乙酯和正丁醇萃取,石油醚部分采用硅胶柱层析、葡聚糖凝胶、反复重结晶、制备型HPLC等多种技术分离纯化,通过理化性质和波谱数据鉴定所得化合物的化学结构.结果 从蟛蜞菊中分离得到12个化合物,分别鉴定为ent-kaura-9(11),16-en-19-oic acid (1),ent-kaura-16-en-19-oic acid (2),15β,16β-epoxy-17-hydroxy-ent-kauran-19-oic acid (3),16α,17-dihydroxy-ent-kauran-19-oic acid (4),16α-hydroxy-ent-kauran-19-oic acid (5),15 α-hydroxy-ent-kaura-16-en-19-oic acid (6),3α-angeloyloxy-9β-hydroxy-ent-kaura-16-en-19-oic acid (7),3α-cinnamoyloxy-9β-hydroxy-ent-kaura-16-en-19-oic acid (8),3α-cinnamoyloxy-17-hydroxy-ent-kaura-15-en-19-oic acid (9),12α-methoxy-ent-kaura-9 (11),16-en-19-oic acid (10),ent-12-oxokaur-9(11),16-en-19-oic acid (11),17-hydroxy-ent-kaura-15-en-19-oic acid (12).结论 化合物3～9为首次从该植物中分离得到,化合物10～12为首次从该属中分离得到.
目的 研究菊科蟛蜞菊屬植物蟛蜞菊的化學成分.方法 蟛蜞菊全草粉碎後用95％乙醇提取,提取物分彆經過石油醚、乙痠乙酯和正丁醇萃取,石油醚部分採用硅膠柱層析、葡聚糖凝膠、反複重結晶、製備型HPLC等多種技術分離純化,通過理化性質和波譜數據鑒定所得化閤物的化學結構.結果 從蟛蜞菊中分離得到12箇化閤物,分彆鑒定為ent-kaura-9(11),16-en-19-oic acid (1),ent-kaura-16-en-19-oic acid (2),15β,16β-epoxy-17-hydroxy-ent-kauran-19-oic acid (3),16α,17-dihydroxy-ent-kauran-19-oic acid (4),16α-hydroxy-ent-kauran-19-oic acid (5),15 α-hydroxy-ent-kaura-16-en-19-oic acid (6),3α-angeloyloxy-9β-hydroxy-ent-kaura-16-en-19-oic acid (7),3α-cinnamoyloxy-9β-hydroxy-ent-kaura-16-en-19-oic acid (8),3α-cinnamoyloxy-17-hydroxy-ent-kaura-15-en-19-oic acid (9),12α-methoxy-ent-kaura-9 (11),16-en-19-oic acid (10),ent-12-oxokaur-9(11),16-en-19-oic acid (11),17-hydroxy-ent-kaura-15-en-19-oic acid (12).結論 化閤物3～9為首次從該植物中分離得到,化閤物10～12為首次從該屬中分離得到.
목적 연구국과팽기국속식물팽기국적화학성분.방법 팽기국전초분쇄후용95％을순제취,제취물분별경과석유미、을산을지화정정순췌취,석유미부분채용규효주층석、포취당응효、반복중결정、제비형HPLC등다충기술분리순화,통과이화성질화파보수거감정소득화합물적화학결구.결과 종팽기국중분리득도12개화합물,분별감정위ent-kaura-9(11),16-en-19-oic acid (1),ent-kaura-16-en-19-oic acid (2),15β,16β-epoxy-17-hydroxy-ent-kauran-19-oic acid (3),16α,17-dihydroxy-ent-kauran-19-oic acid (4),16α-hydroxy-ent-kauran-19-oic acid (5),15 α-hydroxy-ent-kaura-16-en-19-oic acid (6),3α-angeloyloxy-9β-hydroxy-ent-kaura-16-en-19-oic acid (7),3α-cinnamoyloxy-9β-hydroxy-ent-kaura-16-en-19-oic acid (8),3α-cinnamoyloxy-17-hydroxy-ent-kaura-15-en-19-oic acid (9),12α-methoxy-ent-kaura-9 (11),16-en-19-oic acid (10),ent-12-oxokaur-9(11),16-en-19-oic acid (11),17-hydroxy-ent-kaura-15-en-19-oic acid (12).결론 화합물3～9위수차종해식물중분리득도,화합물10～12위수차종해속중분리득도.
