CAJ | 학술논문

目的探讨曲美他嗪治疗不稳定型心绞痛(UAP)的临床疗效.方法将我院2010年7月至2012年6月收治的54例不稳定型心绞痛(UAP)患者随机分为对照组和治疗组,对照组进行常规的β1-受体阻滞剂、硝酸盐制剂、低分子肝素、钙拮抗剂治疗,治疗组在对照组常规治疗的基础上加用曲美他嗪治疗,最后比较两组患者的治疗效果.结果两组患者间心绞痛的治疗效果(81.48％,92.59％)、心电图评定结果(51.85％,74.07％)、缺血发作次数、缺血时间以及缺血面积等方面进行比较,差异有显著性(P＜0.05).结论在常规治疗的基础上加用曲美他嗪可以更好的改善不稳定型心绞痛(UAP)患者的临床症状,而且治疗过程中无严重的不良反应,治疗安全有效,是在治疗不稳定型心绞痛(UAP)中比较先进的治疗方法,值得临床推广和应用.
목적 탐토곡미타진치료불은정형심교통(UAP)적림상료효.방법 장아원2010년7월지2012년6월수치적54례불은정형심교통(UAP)환자수궤분위대조조화치료조,대조조진행상규적β1-수체조체제、초산염제제、저분자간소、개길항제치료,치료조재대조조상규치료적기출상가용곡미타진치료,최후비교량조환자적치료효과.결과 량조환자간심교통적치료효과(81.48％,92.59％)、심전도평정결과(51.85％,74.07％)、결혈발작차수、결혈시간이급결혈면적등방면진행비교,차이유현저성(P＜0.05).결론 재상규치료적기출상가용곡미타진가이경호적개선불은정형심교통(UAP)환자적림상증상,이차치료과정중무엄중적불량반응,치료안전유효,시재치료불은정형심교통(UAP)중비교선진적치료방법,치득림상추엄화응용.
Objective To investigate the clinical efficacy of trimetazidine in the treatment of unstable angina pectoris(UAP).Methods 54 cases of UAP from June 2010 to June 2011 in our hospital were randomly divided into control group and the treatment group,the control group received conventional β 1-blockers,nitrates preparation slow-molecular-weight heparin,calcium antagonists,the treatment group based on the conventional treatment of the control group was given trimetazidine,the two groups were compared with patient outcomes.Results The angina treatment effects of the two groups of patients were 81.48％ and 92.59％,the ECG assessment results were 51.85％ and 74.07％ respectively,ischemic attack times,ischemic time as well as ischemic area of comparison all showed statistical significant differences(P ＜ 0.05).Conclusions On the basis of conventional treatment the plus of trimetazidine can better improve the patients' clinical symptoms of UAP,and has no serious adverse events in the course of treatment,the treatment is safe,effective and quite advanced among similar methods,worthy of clinic promotion and application.