中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2013年
6期
793-796
,共4页
宋旸%蒋昊翔%张璐%刘黎明
宋旸%蔣昊翔%張璐%劉黎明
송양%장호상%장로%류려명
脑瘫%高危儿%贝利婴幼儿量表%磁共振成像
腦癱%高危兒%貝利嬰幼兒量錶%磁共振成像
뇌탄%고위인%패리영유인량표%자공진성상
cerebral palsy (CP)%high-risk infant%Bayley Scales of Infant Development (BSID)%magnetic resonance imaging (MRI)
目的:该研究旨在通过分析脑瘫(CP)常见高危因素构成比例及其与贝利婴幼儿发育量表(BSID)中智力发育指数( MDI)及精神运动发育指数( PDI)之间的相关性,探讨高危因素对患儿智力及运动发育水平的影响。方法收集2011年7月至2012年12月期间在交大一附院儿保科就诊的0~1岁CP高危儿60例。采用BSID Ⅱ评估受试对象智力与精神运动发育水平,用GE公司3.0T磁共振仪进行颅脑MRI检查。将高危因素与精神运动发育水平和MRI结果进行分析。结果 CP高危儿最常见高危因素为早产(41.67%),最常见影像学异常为脑室周围白质软化症(PVL),占46.81%。低出生体重与PVL均于早产儿多见,与足月儿相比有显著性差异(χ2值分别为14.06和4.06,均P<0.05)。 BSID显示受试对象中31.67%智力发育迟滞(MDI≤69),58.33%精神运动发育迟滞(PDI≤69)。 MDI与PDI评级分布区间有显著差异(χ2=11.26,P<0.01)。胎龄与PDI微弱负相关(r=-0.28,P=0.03),但与MDI无相关性(r=-0.11,P>0.05)。结论①早产作为CP常见的高危因素,常合并低出生体重;②早产较足月更容易导致PVL;③与智力障碍相比,CP高危儿运动障碍更为严重。
目的:該研究旨在通過分析腦癱(CP)常見高危因素構成比例及其與貝利嬰幼兒髮育量錶(BSID)中智力髮育指數( MDI)及精神運動髮育指數( PDI)之間的相關性,探討高危因素對患兒智力及運動髮育水平的影響。方法收集2011年7月至2012年12月期間在交大一附院兒保科就診的0~1歲CP高危兒60例。採用BSID Ⅱ評估受試對象智力與精神運動髮育水平,用GE公司3.0T磁共振儀進行顱腦MRI檢查。將高危因素與精神運動髮育水平和MRI結果進行分析。結果 CP高危兒最常見高危因素為早產(41.67%),最常見影像學異常為腦室週圍白質軟化癥(PVL),佔46.81%。低齣生體重與PVL均于早產兒多見,與足月兒相比有顯著性差異(χ2值分彆為14.06和4.06,均P<0.05)。 BSID顯示受試對象中31.67%智力髮育遲滯(MDI≤69),58.33%精神運動髮育遲滯(PDI≤69)。 MDI與PDI評級分佈區間有顯著差異(χ2=11.26,P<0.01)。胎齡與PDI微弱負相關(r=-0.28,P=0.03),但與MDI無相關性(r=-0.11,P>0.05)。結論①早產作為CP常見的高危因素,常閤併低齣生體重;②早產較足月更容易導緻PVL;③與智力障礙相比,CP高危兒運動障礙更為嚴重。
목적:해연구지재통과분석뇌탄(CP)상견고위인소구성비례급기여패리영유인발육량표(BSID)중지력발육지수( MDI)급정신운동발육지수( PDI)지간적상관성,탐토고위인소대환인지력급운동발육수평적영향。방법수집2011년7월지2012년12월기간재교대일부원인보과취진적0~1세CP고위인60례。채용BSID Ⅱ평고수시대상지력여정신운동발육수평,용GE공사3.0T자공진의진행로뇌MRI검사。장고위인소여정신운동발육수평화MRI결과진행분석。결과 CP고위인최상견고위인소위조산(41.67%),최상견영상학이상위뇌실주위백질연화증(PVL),점46.81%。저출생체중여PVL균우조산인다견,여족월인상비유현저성차이(χ2치분별위14.06화4.06,균P<0.05)。 BSID현시수시대상중31.67%지력발육지체(MDI≤69),58.33%정신운동발육지체(PDI≤69)。 MDI여PDI평급분포구간유현저차이(χ2=11.26,P<0.01)。태령여PDI미약부상관(r=-0.28,P=0.03),단여MDI무상관성(r=-0.11,P>0.05)。결론①조산작위CP상견적고위인소,상합병저출생체중;②조산교족월경용역도치PVL;③여지력장애상비,CP고위인운동장애경위엄중。
Objective To investigate the effects of high-risk factors of cerebral palsy ( CP) on psychomoter development levels by analyzing the composition ratio of high-risk factors and the correlations between these factors and the psychomoter development index ( PDI ) and mental development index (MDI) in Bayley Scales of Infant Development (BSID).Methods From July 2011 to December 2013 60 infants with high risk of CP aged 0-1 year visited child health department in the First Affiliated Hospital of Xi ’ an Jiaotong University .The psychomoter and mental development levels were assessed by BSID II , and craniocerebral MRI examination was performed by 3.0T Scanner (GE).The high-risk factors, psychomotor development level and MRI results were analyzed .Results Premature (41.67%) was the most common factor of high-risk CP infants, and PVL (46.81%) was the most common imaging feature .Compared with the mature infants , the low birth weight and PVL were significantly more often in the premature infants (χ2 value was 14.06 and 4.06, respectively, both P<0.05).BSID implied 31.67% of the subjects with sluggish mental development (MDI≤69) and 58.33% with sluggish psychomotor development (PDI≤69), respectively.The grade of MDI and PDI was significantly different in the distribution interval (χ2 =11.26, P<0.01).The fetal age was weakly negatively correlated with PDI (r=-0.28,P=0.03), but not correlated with MDI (r=-0.11, P>0.05).Conclusion As a common high-risk factor of CP, premature is often associated with low birth weight .Compared with term delivery, premature birth is more likely to lead PVL .Movement disorders of CP high-risk infants are more severe than dysgnosia .