CAJ | 학술논문

目的：探讨妊娠期糖尿病对新生儿神经行为发育的影响。方法选择我院2010-03-2013-01新生儿科收治的妊娠期糖尿病产妇所产的新生儿共80例作为观察组，并将同期健康孕妇所生的140例新生儿作为对照组，进行新生儿行为神经测定（NBNA）。结果对照组新生儿NBNA总分均＞35分，而观察组80例新生儿中24例新生儿的NBNA总分＜35分，即NBNA总分异常率为30.00％（24/80）。观察组新生儿的NBNA总分、行为能力、主动肌张力、一般估计等指标均低于对照组且组间差异均具有统计学意义（P＜0.05），低血糖组新生儿的NBNA总分、行为能力、主动肌张力、原始反射以及一般估计等指标均低于血糖正常的新生儿，且组间差异均有统计学意义（ P＜0.05）。结论妊娠期糖尿病孕妇所生新生儿更易出现神经行为发育异常，及时检测新生儿神经行为发育相关情况可有效提高新生儿的预后和生活质量，值得临床应用。
목적：탐토임신기당뇨병대신생인신경행위발육적영향。방법선택아원2010-03-2013-01신생인과수치적임신기당뇨병산부소산적신생인공80례작위관찰조，병장동기건강잉부소생적140례신생인작위대조조，진행신생인행위신경측정（NBNA）。결과대조조신생인NBNA총분균＞35분，이관찰조80례신생인중24례신생인적NBNA총분＜35분，즉NBNA총분이상솔위30.00％（24/80）。관찰조신생인적NBNA총분、행위능력、주동기장력、일반고계등지표균저우대조조차조간차이균구유통계학의의（P＜0.05），저혈당조신생인적NBNA총분、행위능력、주동기장력、원시반사이급일반고계등지표균저우혈당정상적신생인，차조간차이균유통계학의의（ P＜0.05）。결론임신기당뇨병잉부소생신생인경역출현신경행위발육이상，급시검측신생인신경행위발육상관정황가유효제고신생인적예후화생활질량，치득림상응용。
Objective To investigate the effect of gestational diabetes on neonatal neurobehavioral development.Methods Eighty cases of neonatal infants born to mothers with gestational diabetes were taken as the observation group and 140 healthy newborns in the same period as control group.Results In the control group of newborns ,NBNA scores were more than 35 points ,higher than that of the observation group. In the observation group ,NBNA score of 24 cases among the 80 newborns are less than 35 points ,NBNA abnormal score accounted for 30.00% (24/80). In observation group ,newborns NBNA score , behavior ,active muscle tension ,and other indicators were generally lower than those of the control group infants ,the differ-ence between the two groups was statistically significant (P<0.05). In neonatal hypoglycemia group ,NBNA score ,behavior , active muscle tone ,primitive reflexes and general estimates were lower than those of the newborn with normal blood glucose , and the differences was statistically significant (P<0.05).Conclusion Gestational diabetes newborns are more vulnerable to neurobehavioral abnormalities ,and timely detection of neonatal neurobehavioral development can effectively improve neonatal prognosis and quality of life.