CAJ | 학술논문

目的：探讨原发性血小板增多症并发颅内静脉血栓患者临床及影像学表现，提高对该病的认识。方法分析2例原发性血小板增多症并发颅内静脉血栓患者的临床特点、影像学资料，并进行文献回顾。结果该2例患者均为头痛起病，起始症状不明显，血常规检查除血小板明显增高外，白细胞均有轻度增高，JAK2 V617F基因突变阳性，全脑血管造影提示颅内广泛静脉窦未显影，预后良好。结论原发性血小板增多症并发颅内静脉血栓形成患者临床少见，头痛患者发现血小板增多应考虑该病可能。
목적：탐토원발성혈소판증다증병발로내정맥혈전환자림상급영상학표현，제고대해병적인식。방법분석2례원발성혈소판증다증병발로내정맥혈전환자적림상특점、영상학자료，병진행문헌회고。결과해2례환자균위두통기병，기시증상불명현，혈상규검사제혈소판명현증고외，백세포균유경도증고，JAK2 V617F기인돌변양성，전뇌혈관조영제시로내엄범정맥두미현영，예후량호。결론원발성혈소판증다증병발로내정맥혈전형성환자림상소견，두통환자발현혈소판증다응고필해병가능。
Objective To investigate clinical manifestation, image of cerebral venous thrombosis complicated essential thrombocytosis.Methods Clinical and image data were analyzed with a literature review. Results Headache was the common symptom of onset in this two cases, while the initial clinical symptoms was not obvious, in addition to platelets significantly increased, WBC count were mildly increased, JAK2 V617F mutation-positive, venous sinus was not develop by cerebral angiography, and the prognosis was favorable. Conclusion Cerebral venous thrombosis complicated essential thrombocytosis is rare, this disease should be considered if patient with headache and platelet increased.