中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2013年
23期
75-76
,共2页
宫颈癌%放射治疗%高剂量短程放疗%计量体积直方图分析%外照射放疗
宮頸癌%放射治療%高劑量短程放療%計量體積直方圖分析%外照射放療
궁경암%방사치료%고제량단정방료%계량체적직방도분석%외조사방료
Uterine cervical cancer%Radiotherapy%High-dose-rate brachytherapy%External beam radiotherapy
目的：探讨短程放疗治疗宫颈癌患者摆位改变对膀胱和直肠HR-CTVD90的影响。方法接受外照射和高剂量率ICBT治疗的58例宫颈癌患者纳入研究，采用其中一种ICBT，行盆腔CT扫描并采集HR-CTV数据。这些病例分为标准剂量组和适应剂量组（覆盖HR-CTV照射6Gy等剂量线）。每个过程评估HR-CTVD90和摆位改变。结果标准剂量组前三次ICBT的HR-CTVD90随摆位改变呈递增趋势，而适应剂量组相对恒定。结论肿瘤体积摆位改变和影像引导的适应性短程放疗可在膀胱和直肠能接受的范围内改善HR-CTV剂量选择。
目的：探討短程放療治療宮頸癌患者襬位改變對膀胱和直腸HR-CTVD90的影響。方法接受外照射和高劑量率ICBT治療的58例宮頸癌患者納入研究，採用其中一種ICBT，行盆腔CT掃描併採集HR-CTV數據。這些病例分為標準劑量組和適應劑量組（覆蓋HR-CTV照射6Gy等劑量線）。每箇過程評估HR-CTVD90和襬位改變。結果標準劑量組前三次ICBT的HR-CTVD90隨襬位改變呈遞增趨勢，而適應劑量組相對恆定。結論腫瘤體積襬位改變和影像引導的適應性短程放療可在膀胱和直腸能接受的範圍內改善HR-CTV劑量選擇。
목적：탐토단정방료치료궁경암환자파위개변대방광화직장HR-CTVD90적영향。방법접수외조사화고제량솔ICBT치료적58례궁경암환자납입연구，채용기중일충ICBT，행분강CT소묘병채집HR-CTV수거。저사병례분위표준제량조화괄응제량조（복개HR-CTV조사6Gy등제량선）。매개과정평고HR-CTVD90화파위개변。결과표준제량조전삼차ICBT적HR-CTVD90수파위개변정체증추세，이괄응제량조상대항정。결론종류체적파위개변화영상인도적괄응성단정방료가재방광화직장능접수적범위내개선HR-CTV제량선택。
Objective To expolre the effect of interfractional changes on HR-CTV D90 during brachytherapy for uterine cervical cancer patients. Methods 58 patients received EBRT and HDR ICBT. For one ICBT applications, a pelvic CT scan was performed and the HR-CTV was recorded. These patients were divided into standard dose group and adaptive dose group.The HR-CTV D90 was evaluated and analyzed as interfractional changes. Results The interfractional changes of the HR-CTV D90 in the standard dose group showed an increase during former three times ICBT, those of the adaptive dose group remained almostly constant. Conclusion Image-guided adaptive brachytherapy based on interfractional tumor volume change might improve the dose to the HR-CTV.
