CAJ | 학술논문

膜性肾病是常见的原发性肾小球疾病，是以肾小球脏层上皮细胞下免疫复合物弥漫性沉积、基底膜增厚伴钉突形成为其病理学特征。其发病机制复杂，近年来，随着对足细胞的一些标志分子的深入研究，证实足细胞的异常与蛋白尿的产生密切相关。在此对足细胞的异常与膜性肾病的发生发展等相关进展作简单综述。
막성신병시상견적원발성신소구질병，시이신소구장층상피세포하면역복합물미만성침적、기저막증후반정돌형성위기병이학특정。기발병궤제복잡，근년래，수착대족세포적일사표지분자적심입연구，증실족세포적이상여단백뇨적산생밀절상관。재차대족세포적이상여막성신병적발생발전등상관진전작간단종술。
Membranous nephropathy is a common primary glomerular disease. The pathological features is based on the deposition of immune complexes diffuse glomerular visceral epithelial cells and basement membrane thickening with spikes. Its pathogenesis is complicated. In recent years,the in-depth study of markers of podocytes confirmed that podocytes is closely related to the generation of abnormal proteinuria. This thesis overviewed the progress on podocyte abnormalities of membranous nephropathy development.