CAJ | 학술논문

目的：通过分析降钙素原（PCT）与C反应蛋白（CRP）联合检测在临床感染性疾病中的应用，证明PCT和CRP联合检测在临床感染性疾病中具有重要诊断价值。方法对我院2012年1月~2013年1月收治的40例病毒感染性疾病患者、80例细菌感染性疾病患者以及40名健康者分别用免疫荧光分析法和免疫比浊法检测其降钙素原和C反应蛋白，然后对检测结果进行分析。结果重症细菌感染组（Ⅰ组）、一般细菌感染组（Ⅱ组）降钙素原水平明显高于病毒感染组（Ⅲ组）及对照组（Ⅳ组），差异有统计学意义（P＜0.05）；细菌感染组PCT与CRP之间呈正相关关系，而病毒感染组PCT与CRP没有关联性。结论降钙素原与C反应蛋白都可用来诊断临床感染性疾病，且降钙素原相比C反应蛋白在细菌感染中更有优势，在临床感染性疾病中联合检测PCT与CRP效果更佳，具有很大的诊断价值。
목적：통과분석강개소원（PCT）여C반응단백（CRP）연합검측재림상감염성질병중적응용，증명PCT화CRP연합검측재림상감염성질병중구유중요진단개치。방법대아원2012년1월~2013년1월수치적40례병독감염성질병환자、80례세균감염성질병환자이급40명건강자분별용면역형광분석법화면역비탁법검측기강개소원화C반응단백，연후대검측결과진행분석。결과중증세균감염조（Ⅰ조）、일반세균감염조（Ⅱ조）강개소원수평명현고우병독감염조（Ⅲ조）급대조조（Ⅳ조），차이유통계학의의（P＜0.05）；세균감염조PCT여CRP지간정정상관관계，이병독감염조PCT여CRP몰유관련성。결론강개소원여C반응단백도가용래진단림상감염성질병，차강개소원상비C반응단백재세균감염중경유우세，재림상감염성질병중연합검측PCT여CRP효과경가，구유흔대적진단개치。
Objective To analyze the procalcitonin (PCT) and C reactive protein (CRP)in the combined detection of diseases in clinical infection,proves that the combined detection of PCT and CRP has important clinical value in diagnosis of infectious diseases. Methods 40 cases of the virus in our hospital from 2012 January to 2013January were infectious disease,80 cases of bacterial infection disease patients and 40 healthy subjects were used in immunofluorescence analysis and immunenephelometry procalcitonin and C reactive protein,and then the test results were analyzed. Results Severe bacterial infection group (Zu),the general bacterial infection group(Group II) procalcitonin levels were significantly higher than that ofviral infection group (Group III) and control group (Zu),the difference was statistically significant (P < 0.05); the positive correlation between bacterial infection group PCTand CRP,and group PCT with no relationship between CRP virus infection. Conclusion The procalcitonin and C reactive protein can be used for clinical diagnosis of infectious diseases,and procalcitonin compared with C reactive protein more in bacterial infection in clinical infection,combined detection of PCT and CRP diseasebetter effect,has great diagnostic value.