CAJ | 학술논문

目的：观察地佐辛用于全麻苏醒期的临床效果。方法将全麻妇科腹腔镜手术60例随机分为对照组(A组)和地佐辛组(D组)各30例。两组均采用气管插管静脉麻醉，手术结束前约20min给予D组肌注地佐辛0.1mg/kg，A组不给任何药物。比较两组患者的苏醒时间、拔管时间，苏醒前、拔管时、拔管后10minMAP、HR的变化，记录两组患者拔管后疼痛、寒战及躁动不良反应的发生例数。结果两组苏醒时间、拔管时间、苏醒前MAP、HR的变化无统计学差异(P >0.05)，两组患者拔管时、拔管后10minMAP、HR的变化和术后发生寒战、躁动的例数及镇痛评分有统计学差异(P <0.05)。结论手术结束前20min肌注地佐辛能有效抑制拔管期血流动力学的波动，减少术后恶心呕吐、寒战、躁动的发生率，且不影响术后苏醒。
목적：관찰지좌신용우전마소성기적림상효과。방법장전마부과복강경수술60례수궤분위대조조(A조)화지좌신조(D조)각30례。량조균채용기관삽관정맥마취，수술결속전약20min급여D조기주지좌신0.1mg/kg，A조불급임하약물。비교량조환자적소성시간、발관시간，소성전、발관시、발관후10minMAP、HR적변화，기록량조환자발관후동통、한전급조동불량반응적발생례수。결과량조소성시간、발관시간、소성전MAP、HR적변화무통계학차이(P >0.05)，량조환자발관시、발관후10minMAP、HR적변화화술후발생한전、조동적례수급진통평분유통계학차이(P <0.05)。결론수술결속전20min기주지좌신능유효억제발관기혈류동역학적파동，감소술후악심구토、한전、조동적발생솔，차불영향술후소성。
Objective Observation of clinical effect of dezocine for general anesthesia recovery period. Methods Choice of gynecological laparoscopic operation of general anesthesia in 60 cases, were randomly divided into two groups, control group(group A) and dezocine group(group D), 30 cases in each group. Two groups were treated with tracheal intubation general anesthesia, operation end 20min prior to D group intramuscular injection of dezocine 0.1mg/kg, A group was not given any drug. Comparison of two groups of patients recovery time, extubation time, before awakening, extubation, 10min after extubation MAP, HR changes, the two groups were recorded after extubation pain, chills and agitation in the incidence of adverse reactions. Results Recovery time, extubation time, changes of MAP, HR before awakening in the two groups showed no significant difference(P >0.05), and the two group of patient extubation, 10min after extubation MAP, HR changes and postoperative shivering, agitation and pain scores weretatistically significant(P <0.05). Conclusion Before the end of operation 20min intramuscular injection of dezocine can effectively inhibit the extubation period hemodynamic fluctuations, reduce postoperative nausea and vomiting, chills, the incidence of agitation rate, and does not affect the postoperative recovery.