CAJ | 학술논문

目的：观察重度慢性阻塞性肺疾病(COPD)合并营养不良患者发生率，评价早期肠内营养治疗的疗效。方法112例重度COPD患者随机分为肠内营养组(EN组)、肠外营养组(PN组)，均在营养支持前及营养支持1周后观察体重指数(IBM)、血清白蛋白、血红蛋白、总淋巴细胞计数、SGRQ评分。结果治疗后两组血清白蛋白、血红蛋白、淋巴细胞总数、SGRQ评分与治疗前相比有明显改善(P <0.05)；治疗后两组体重指数较治疗前无明显改善(P >0.05)，两组治疗前后SGRQ评分有显著差异(P <0.05)。结论 PN及PN均能改善重度COPD患者的营养状态，PN在临床疗效上优于PN。
목적：관찰중도만성조새성폐질병(COPD)합병영양불량환자발생솔，평개조기장내영양치료적료효。방법112례중도COPD환자수궤분위장내영양조(EN조)、장외영양조(PN조)，균재영양지지전급영양지지1주후관찰체중지수(IBM)、혈청백단백、혈홍단백、총림파세포계수、SGRQ평분。결과치료후량조혈청백단백、혈홍단백、림파세포총수、SGRQ평분여치료전상비유명현개선(P <0.05)；치료후량조체중지수교치료전무명현개선(P >0.05)，량조치료전후SGRQ평분유현저차이(P <0.05)。결론 PN급PN균능개선중도COPD환자적영양상태，PN재림상료효상우우PN。
Objective To observe the incidence of patients with severe COPD accompanied malnutrition and evaluate the effect of early venous support therapy. Methods 112 patients with severe COPD patients were randomly divided into enteral and fewer ten patients experienced septic complications(EN group) and parenteral and fewer ten patients experienced septic complications(PN group), two groups of patients in the nutrition support and nutrition support after 1 week before the observation of body mass index(IBM), serum albumin, hemoglobin, total lymphocyte count, SGRQ scores. Results Serum albumin, hemoglobin, total number of lymphocytes, SGRQ scores of two groups after treatment have significant differences compared with pretreatment(P <0.05); Two groups of body mass index after treatment no significant improvement compared with pretreatment(P >0.05). Two groups of contrast SGRQ scores before and after treatment respectively have significant differences compared with pretreatment(P <0.05). Conclusion Enteral nutrition and parenteral nutrition can improve the nutritional status of patients with severe COPD, parenteral nutrition is better than that of enteral nutrition on clinical curative effect.