CAJ | 학술논문

目的：探讨水飞蓟宾磷脂复合物联合阿德福韦酯治疗慢性乙肝的疗效。方法将56例慢性乙肝患者分为两组，对照组仅用阿德福韦酯治疗慢性乙肝，实验组在使用阿德福韦酯的基础上增加使用水飞蓟宾磷脂复合物。结果经治疗12周后，治疗组和对照组在ALT、AST、ALT/AST、血清白蛋白（Alb）、总胆红素（TBIL）等反映肝功能的指标比较差异有显著性（P＜0.05）；治疗组总有效率为89.3%，对照组总有效率为78.6%，两组比较差异有显著性（P＜0.05）。结论水飞蓟宾磷脂复合物联合阿德福韦酯治疗慢性乙肝疗效比单独使用阿德福韦酯效果更好。
목적：탐토수비계빈린지복합물연합아덕복위지치료만성을간적료효。방법장56례만성을간환자분위량조，대조조부용아덕복위지치료만성을간，실험조재사용아덕복위지적기출상증가사용수비계빈린지복합물。결과경치료12주후，치료조화대조조재ALT、AST、ALT/AST、혈청백단백（Alb）、총담홍소（TBIL）등반영간공능적지표비교차이유현저성（P＜0.05）；치료조총유효솔위89.3%，대조조총유효솔위78.6%，량조비교차이유현저성（P＜0.05）。결론수비계빈린지복합물연합아덕복위지치료만성을간료효비단독사용아덕복위지효과경호。
Objective To research an discuss the clinical efficacy of siIybin-phosphatidylcholine complex and Adefovir Dipivoxil in patients with chronic hepatitis B.Methods 56 patients were grouped with one using Adefovir Dipivoxil only,and the other using Adefovir Dipivoxil and siIybin-phosphatidylcholine complex.Results After 12 weeks of treatment,the differences of treatment and control groups in ALT、AST、ALT / AST,serum albumin(Alb),total bilirubin(TBIL)which are indicators of liver function was significant(P<0.05);The total effective rate of the treatment group was 89.3%, while the total effective rate of the control group was 78.6%, the difference was statisticaly significant(P<0.05).Conclusion Silybin phospholipid complexes combined with adefovir dipivoxil for the treatment of chronic hepatitis B is better than the single use of adefovir dipivoxil.