CAJ | 학술논문

为了实现对人眼视网膜的高分辨率成像，解决偏振能量损失、成像视场小和普适性差等问题，对液晶自适应光学技术及其在人眼视网膜成像中的应用进行了研究。通过开环光路的设计方案，避免了闭环液晶自适应系统的偏振光能量损失；在光路中加入可变视场光阑，利用小视场照明进行波前探测、大视场照明进行像差校正和成像的方法扩大了成像视场；使用脉冲光照明的方案减小曝光量；通过偏振光照明提高能量利用率、等效无穷远视标配合补偿镜以及改进后的视标提高盯视稳定性等一系列方法，提高系统普适性。校正后成像的清晰度和对比度获得了明显提高；高分辨率眼底成像视场直径从200μm扩大到500μm；曝光量减小到原来的1/2～1/3；对前期难以获得清晰成像的样本，取得了效果良好的视网膜视觉细胞自适应图像。
위료실현대인안시망막적고분변솔성상，해결편진능량손실、성상시장소화보괄성차등문제，대액정자괄응광학기술급기재인안시망막성상중적응용진행료연구。통과개배광로적설계방안，피면료폐배액정자괄응계통적편진광능량손실；재광로중가입가변시장광란，이용소시장조명진행파전탐측、대시장조명진행상차교정화성상적방법확대료성상시장；사용맥충광조명적방안감소폭광량；통과편진광조명제고능량이용솔、등효무궁원시표배합보상경이급개진후적시표제고정시은정성등일계렬방법，제고계통보괄성。교정후성상적청석도화대비도획득료명현제고；고분변솔안저성상시장직경종200μm확대도500μm；폭광량감소도원래적1/2～1/3；대전기난이획득청석성상적양본，취득료효과량호적시망막시각세포자괄응도상。
In order to realize high resolution retinal imaging , the technique of Liquid Crystal Adaptive Optics ( LC-AO) and its utilize in retinal imaging is under investigation .Problems are settled in the research such as energy loss by polarization , limitation on field of view ( FOV) and universality of LC-AO system in retinal ima-ging.Open-loop adaptive optics system is introduced to avoid the energy loss by polarization in closed -loop system.View field of imaging system is expanded by adhibition of an alterable diaphragm .Exposure ratio is reduced by a pulsed light source .Illumination is polarized to increase energy efficiency .Trial lens and dynam-ic, advanced target at infinite are used to increase the stability of pupil and reduce the impact of individual differences on human-eyes.Definition and contrast of images after correction are remarkably increased .FOV is enhanced from 200 μm to 500 μm.Exposure ratio is reduced to 1/2 ~1/3.High definition images are taken from samples with low resolution before .Most problems of LC-AO system for high resolution retinal ima-ging are settled .