CAJ | 학술논문

目的：探讨老年哮喘患者诱导痰中EC P水平及其与气管炎症的关系。方法：测定发作期老年支气管哮喘患者舒利迭治疗前后诱导痰EC P水平。结果：哮喘老人在急性期痰液中EC P水平显著增高（P＜0．05）；急性期痰液ECP含量与PEF（％）呈一种负相关趋势；治疗前后痰液中EC P水平的变化幅度较之血清EC P有极显著性差异（ P＜0．01）。结论：老年支气管哮喘急性期患者痰液EC P水平升高，痰液中EC P的测试为哮喘病的体外监测提供了一种有效手段。
목적：탐토노년효천환자유도담중EC P수평급기여기관염증적관계。방법：측정발작기노년지기관효천환자서리질치료전후유도담EC P수평。결과：효천노인재급성기담액중EC P수평현저증고（P＜0．05）；급성기담액ECP함량여PEF（％）정일충부상관추세；치료전후담액중EC P수평적변화폭도교지혈청EC P유겁현저성차이（ P＜0．01）。결론：노년지기관효천급성기환자담액EC P수평승고，담액중EC P적측시위효천병적체외감측제공료일충유효수단。
Objective:To investigate the level of induced sputum ECP in elderly patients with asthma bron-chial ,and analysis of the relationship between airway inflammation .Methods :We selected moderate and severe eld-erly patients with asthma bronchial ,using enzyme-linked immunofluorescent assay (ELIFA )detected by sputum ECP concentration .Results :sputum ECP in untreated asthma bronchial patients was significantly higher than that in treated asthma bronchial patients .The result of this study showed a negative correlated between sputum ECP and PEF(% ) in untreated asthma bronchial patients .The changes of sputum ECP between untreaded and treaded pa-tients were markedly higher than that of plasma ECP .Conclusion:These results indicated that sputum ECP is high-er in asthma bronchial patients without treatment ,Determination sputum ECP For asthma in vitro monitoring pro-vides an effective means .