CAJ | 학술논문

目的：探讨左卡尼汀对儿童病毒性心肌炎（VMC）心率减速力（DC）的影响。方法：将40例病毒性心肌炎患儿设为治疗组，每天给予左卡尼汀100mg/kg，静脉滴注，疗程14d；对照组为30例健康体检儿童。对所有患儿在治疗前后以及对照组儿童进行24h动态心电图检查，应用DC处理软件，离线计算DC值。结果：治疗组治疗前DC值较对照组明显降低（P＜0．05）。治疗后DC值有明显改善，与治疗前比较有显著性差异（P＜0．05），与对照组比较无显著性差异（P＞0．05）。结论：病毒性心肌炎患儿有迷走神经功能受损，左卡尼汀可改善迷走神经功能，对心肌有保护作用。
목적：탐토좌잡니정대인동병독성심기염（VMC）심솔감속력（DC）적영향。방법：장40례병독성심기염환인설위치료조，매천급여좌잡니정100mg/kg，정맥적주，료정14d；대조조위30례건강체검인동。대소유환인재치료전후이급대조조인동진행24h동태심전도검사，응용DC처리연건，리선계산DC치。결과：치료조치료전DC치교대조조명현강저（P＜0．05）。치료후DC치유명현개선，여치료전비교유현저성차이（P＜0．05），여대조조비교무현저성차이（P＞0．05）。결론：병독성심기염환인유미주신경공능수손，좌잡니정가개선미주신경공능，대심기유보호작용。
Objective :To study the effect of Levocarnitine on deceleration capacity of heart rate in children with viral myocarditis .Methods :40 cases of children with viral myocarditis as the treatment group ,treated with Le-vocarnitine injection(100mg/kg) ,for 14 days;the control group of 30 healthy children .The DC in all patients before and after treatment and control group children was measured using digitized 24 hours ECG Holter recording .Re-sults :Compared with the control group ,the treatment group before treatment ,DC value decreased ,the difference was statistically significant ( P< 0 .05 ) .After treatment ,DC value was significantly improved ,compared with before treatment ,the difference was statistically significant (P<0 .05) ,and the control group had no significant difference (P>0 .05) .Conclusion :It is suggested that there is vagus nerve damage in children with viral myocarditis ,Levocar-nitine can improve the vagus nerve function ,and it has a protective effect on myocardial .