CAJ | 학술논문

目的：研究胃癌中医药治疗的用药规律。方法：通过胃癌结构化临床信息采集系统，采集了2008~2011年广安门医院肿瘤科的胃癌住院病例111例，运用无尺度网络方法，从中药的功效、种类、配伍关系等方面，探讨胃癌中医治疗用药规律。结果：通过对111例胃癌住院病例的分析总结，发现治疗胃癌多采用扶正为主的方剂，以六君子汤使用最多，组方时补虚药居于首位，且以补气药为主，其次清热药、利水渗湿、活血化瘀药、消食药、理气药。治疗胃癌的核心处方用药为茯苓、党参、黄芪、陈皮、枳壳、蜂房等，中医治法及辨证用药随治疗阶段和病程阶段而有所变化。结论：无尺度网络分析方法对分析胃癌中医治疗的用药规律有一定意义。
목적：연구위암중의약치료적용약규률。방법：통과위암결구화림상신식채집계통，채집료2008~2011년엄안문의원종류과적위암주원병례111례，운용무척도망락방법，종중약적공효、충류、배오관계등방면，탐토위암중의치료용약규률。결과：통과대111례위암주원병례적분석총결，발현치료위암다채용부정위주적방제，이륙군자탕사용최다，조방시보허약거우수위，차이보기약위주，기차청열약、이수삼습、활혈화어약、소식약、리기약。치료위암적핵심처방용약위복령、당삼、황기、진피、지각、봉방등，중의치법급변증용약수치료계단화병정계단이유소변화。결론：무척도망락분석방법대분석위암중의치료적용약규률유일정의의。
This article was aimed to study medication rules of traditional Chinese medicine (TCM) in the treatment of gastric cancer. The history information of 111 hospitalized cases from 2008 to 2011 was collected from the Department of Oncology of Guang'anmen Hospital with the clinical collection system. The medication rules in the treatment of gastric cancer by TCM were explored by the scale-free network analysis from several aspects, such as effects, classifications and compatibility relations of Chinese medicine. The analysis result of 111 gastric cancer cases showed that strengthening the body resistance was the main treatment principle. Liujunzi decoction was the most frequently used prescription. In TCM compatibility, deficiency-nourishing herbs were the main ingredients, especially"qi-supplementing" herbs which take the first place in the prescription. And the heat-reducing herbs, dampness-eliminating herbs, blood-activating and stasis-eliminating herbs, food stagnation resolving herbs and qi regulation herbs were also used in the combination. Core herbs in the prescription for the treatment of gastric cancer were Tuckahoe, Codonopsis pilosula, Astragalus root, Pericarpium Citri Reticulatae, Fructus Aurantii, Nidus Vespae and etc. TCM treatment, syndrome differentiation and medication are varied according to different therapeutic stages and disease stages. The result showed that scale-free network analysis had certain significance in the understanding of medication rules of TCM treatment of gastric cancer.