河北中医
河北中醫
하북중의
HEBEI JORNAL OF TRADITIONAL CHINESE MEDICINE
2014年
1期
17-18,21
,共3页
肾疾病%并发症%肾透析%红细胞生成素,重组%中西医结合疗法
腎疾病%併髮癥%腎透析%紅細胞生成素,重組%中西醫結閤療法
신질병%병발증%신투석%홍세포생성소,중조%중서의결합요법
Kidney disease%Complications%Kidney dialysis%Erythropoietin%Recombinant%Combined therapy of Chinese and Western medicine
目的：观察益气生血汤辅助重组人促红细胞生成素（ rhEPO ）治疗尿毒症行血液透析患者肾性贫血临床疗效。方法将36例行维持性血液透析治疗的尿毒症肾性贫血患者随机分为2组。对照组18例单用rhEPO治疗，治疗组18例在对照组治疗基础上加用益气生血汤。2组均治疗8周后观察临床疗效，并观察2组治疗前后血红蛋白（ Hgb）、红细胞比容（ HCT）的指标变化及每周rhEPO的平均用量。结果2组治疗后Hgb、HCT与本组治疗前比较均增高（P＜0．01），且治疗后治疗组Hgb、HCT高于对照组（P＜0．01）。治疗组rhEPO每周平均用量较对照组少（ P＜0．01）。治疗组血压升高发生率低于对照组（ P＜0．05）。治疗组总有效率94．44％，对照组总有效率77．78％，2组比较差异有统计学意义（ P＜0．05），治疗组临床疗效优于对照组。结论益气生血汤辅助rhEPO治疗尿毒症行血液透析患者肾性贫血疗效确切。
目的：觀察益氣生血湯輔助重組人促紅細胞生成素（ rhEPO ）治療尿毒癥行血液透析患者腎性貧血臨床療效。方法將36例行維持性血液透析治療的尿毒癥腎性貧血患者隨機分為2組。對照組18例單用rhEPO治療，治療組18例在對照組治療基礎上加用益氣生血湯。2組均治療8週後觀察臨床療效，併觀察2組治療前後血紅蛋白（ Hgb）、紅細胞比容（ HCT）的指標變化及每週rhEPO的平均用量。結果2組治療後Hgb、HCT與本組治療前比較均增高（P＜0．01），且治療後治療組Hgb、HCT高于對照組（P＜0．01）。治療組rhEPO每週平均用量較對照組少（ P＜0．01）。治療組血壓升高髮生率低于對照組（ P＜0．05）。治療組總有效率94．44％，對照組總有效率77．78％，2組比較差異有統計學意義（ P＜0．05），治療組臨床療效優于對照組。結論益氣生血湯輔助rhEPO治療尿毒癥行血液透析患者腎性貧血療效確切。
목적：관찰익기생혈탕보조중조인촉홍세포생성소（ rhEPO ）치료뇨독증행혈액투석환자신성빈혈림상료효。방법장36례행유지성혈액투석치료적뇨독증신성빈혈환자수궤분위2조。대조조18례단용rhEPO치료，치료조18례재대조조치료기출상가용익기생혈탕。2조균치료8주후관찰림상료효，병관찰2조치료전후혈홍단백（ Hgb）、홍세포비용（ HCT）적지표변화급매주rhEPO적평균용량。결과2조치료후Hgb、HCT여본조치료전비교균증고（P＜0．01），차치료후치료조Hgb、HCT고우대조조（P＜0．01）。치료조rhEPO매주평균용량교대조조소（ P＜0．01）。치료조혈압승고발생솔저우대조조（ P＜0．05）。치료조총유효솔94．44％，대조조총유효솔77．78％，2조비교차이유통계학의의（ P＜0．05），치료조림상료효우우대조조。결론익기생혈탕보조rhEPO치료뇨독증행혈액투석환자신성빈혈료효학절。
Objective To observe the treatment of uremic hemodialysis patients with renal anemia by Yiqishengxue decoction assisted with recombinant human erythropoietin ( rhEPO) .Methods 36 uremic hemodialysis patients with renal anemia were randomly divided into two groups .18 cases in control group received rhEPO .18 cases in treatment group received Yiqishengxue decoction on the basis of control group treatment .The therapeutic effect was observed after 8 weeks of treatment .The changes of Hb and HCT ,usage of rhEPO were recorded .Results The levels of Hb and HCT after treatment were increased as compared with those before treatment in two groups (P<0.01).The levels of Hb and HCT in treatment group were higher than those in control group (P<0.01).The average amount per week of RhEPO in treatment group was decreased as compared with that in the control group (P<0.01).The inci-dence of high blood pressure in treatment group was less than that in the control group (P<0.05).The total effective rate in treatment group(94.44%)was superior to that in control group (77.78%,P<0.05).Conclusion Yiqish-engxue decoction assisted with recombinant human erythropoietin has definite effect on the treatment of uremic hemo -dialysis patients with renal anemia .
