CAJ | 학술논문

目的：观察法舒地尔治疗非动脉炎性缺血性视神经病变的临床效果。 　　方法：自2012-03/2013-06收治的缺血性视神经病变患者70例随机分为观察组（法舒地尔治疗组）和对照组（常规治疗组）各35例，治疗周期均为4 wk ，观察比较两组的最佳矫正视力和视野。 　　结果：观察组最佳矫正视力总有效率为86％；对照组总有效率为57％，两组比较差异显著，具有统计学意义（ P＜0.05）。观察组视野好转率为83％，对照组视野好转率为57％，两组比较差异显著，具有统计学意义（ P＜0．05）。 　　结论：法舒地尔治疗非动脉炎性缺血性视神经病变效果优于传统药物。
목적：관찰법서지이치료비동맥염성결혈성시신경병변적림상효과。 　　방법：자2012-03/2013-06수치적결혈성시신경병변환자70례수궤분위관찰조（법서지이치료조）화대조조（상규치료조）각35례，치료주기균위4 wk ，관찰비교량조적최가교정시력화시야。 　　결과：관찰조최가교정시력총유효솔위86％；대조조총유효솔위57％，량조비교차이현저，구유통계학의의（ P＜0.05）。관찰조시야호전솔위83％，대조조시야호전솔위57％，량조비교차이현저，구유통계학의의（ P＜0．05）。 　　결론：법서지이치료비동맥염성결혈성시신경병변효과우우전통약물。
AIM:To evaluate the clinical effects of fasudil therapy on nonarteritic anterior ischemic optic neuropathy ( NAION) . METHODS:Seventy eyes of 70 patients with NAION in our hospital were collected and randomly divided into treatment group ( 35 patients ) which was intravenously injected fasudil, and control group ( 35 patients ) which was intravenously injected composite salvia miltiorrhiza injection.At the 4wk of follow-up, the best corrected visual acuity ( BCVA) and visual field were observed and compared. RESULTS:The total effective rate of BCVA in treatment group was 86%, in control group was 57%.The difference in two groups had statistical significance (P<0.05).The improvement rate of visual field in treatment group was 83%and in control group was 57%.The difference in two groups had statistical significance ( P<0.05) CONCLUSION:The clinical effects of fasudil on NAION are better than conventional medication.