国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
2期
352-353
,共2页
糖尿病视网膜病变%激光光凝%羟苯磺酸钙
糖尿病視網膜病變%激光光凝%羥苯磺痠鈣
당뇨병시망막병변%격광광응%간분광산개
diabetic retinopathy%laser photocoagulation%calcium dobesilate
目的:观察577 nm激光联合羟苯磺酸钙治疗糖尿病视网膜病变( diabetic retinopathy ,DR)的临床疗效。<br> 方法:选取2012-01/06来我院就诊的DR患者104例180眼做为研究对象,采用随机数字表法将其分为三组:药物治疗组(32例56眼)和激光治疗组(50例86眼)及联合治疗组(22例38眼),分别给予药物治疗、577 nm激光治疗、药物治疗联合577 nm激光治疗,随访6 mo后,对比患者在治疗前后视力及眼底的改善程度。<br> 结果:激光治疗组的视力改善程度明显高于药物治疗组,眼底毛细血管无灌注区消失及新生血管消退率高于药物治疗组,差异均有统计学意义(P<0.05);联合治疗组效果好于单因素治疗组,差异均有统计学意义(P<0.05)。<br> 结论:577 nm激光联合联合羟苯磺酸钙治疗DR的疗效确切,值得在临床更多应用。
目的:觀察577 nm激光聯閤羥苯磺痠鈣治療糖尿病視網膜病變( diabetic retinopathy ,DR)的臨床療效。<br> 方法:選取2012-01/06來我院就診的DR患者104例180眼做為研究對象,採用隨機數字錶法將其分為三組:藥物治療組(32例56眼)和激光治療組(50例86眼)及聯閤治療組(22例38眼),分彆給予藥物治療、577 nm激光治療、藥物治療聯閤577 nm激光治療,隨訪6 mo後,對比患者在治療前後視力及眼底的改善程度。<br> 結果:激光治療組的視力改善程度明顯高于藥物治療組,眼底毛細血管無灌註區消失及新生血管消退率高于藥物治療組,差異均有統計學意義(P<0.05);聯閤治療組效果好于單因素治療組,差異均有統計學意義(P<0.05)。<br> 結論:577 nm激光聯閤聯閤羥苯磺痠鈣治療DR的療效確切,值得在臨床更多應用。
목적:관찰577 nm격광연합간분광산개치료당뇨병시망막병변( diabetic retinopathy ,DR)적림상료효。<br> 방법:선취2012-01/06래아원취진적DR환자104례180안주위연구대상,채용수궤수자표법장기분위삼조:약물치료조(32례56안)화격광치료조(50례86안)급연합치료조(22례38안),분별급여약물치료、577 nm격광치료、약물치료연합577 nm격광치료,수방6 mo후,대비환자재치료전후시력급안저적개선정도。<br> 결과:격광치료조적시력개선정도명현고우약물치료조,안저모세혈관무관주구소실급신생혈관소퇴솔고우약물치료조,차이균유통계학의의(P<0.05);연합치료조효과호우단인소치료조,차이균유통계학의의(P<0.05)。<br> 결론:577 nm격광연합연합간분광산개치료DR적료효학절,치득재림상경다응용。
AIM:To investigate the effects of photocoagulation with 577 -nm laser combined with calcium dobesilate on diabetic retinopathy( DR) . <br> METHODS: From January 2012 to June 2012, 104 patients ( 180 eyes ) with diabetic retinopathy were selected and randomly divided into medicine group, 577-nm laser group and combined treatment group. The medicine group consisting of 32 cases (56 eyes) received calcium dobesilate, and 577-nm laser group including 50 cases ( 86 eyes ) were treated by photocoagulation with 577-nm laser. And 22 cases ( 38 eyes ) of combined treatment group were treated with both methods above. The follow -up period was 6mo. The effects were evaluated by visual acuity and fundus fluorescein angiography ( FFA) . <br> RESULTS: Compared with medicine group, the rate of disappeared retinal capillary nonperfusion areas and regressed neovascularization was higher in 577-nm laser group.And the visual acuity of 577-nm laser group was improved significantly more than the medicine group. The difference was statistically significant (P<0.05).The combined treatment group achieved more favorable results than every single treatment group (P<0.05). <br> CONCLUSION: Photocoagulation with 577-nm laser combined with calcium dobesilate is effective for diabetic retinopathy and it is worth making more application in clinic.