CAJ | 학술논문

目的：观察加减驻景方治疗高度近视黄斑出血的临床疗效。 　　方法：将患者42例42眼根据治疗方法不同分为加减驻景方组25例25眼，用加减驻景方治疗；加减驻景方联合雷珠单抗组（联合组）17例17眼，采用玻璃体腔内注射雷珠单抗同时给予加减驻景方进行治疗，治疗前后采用OCT检测中心视网膜厚度，随访3mo，观察两组的疗效。 　　结果：联合组在治疗3 mo后总有效率达到82％，加减驻景方组总有效率达到60％；联合组在治疗3 mo后眼底出血吸收总有效率达88％，加减驻景方组的有效率达64％；在降低中心视网膜厚度方面，各组治疗后与治疗前比较及两组组间比较，差异均有统计学意义（P＜0．05）。 　　结论：中药加减驻景方能有效地延缓病情的发展、减少病变的反复次数及提高患者的视力。
목적：관찰가감주경방치료고도근시황반출혈적림상료효。 　　방법：장환자42례42안근거치료방법불동분위가감주경방조25례25안，용가감주경방치료；가감주경방연합뢰주단항조（연합조）17례17안，채용파리체강내주사뢰주단항동시급여가감주경방진행치료，치료전후채용OCT검측중심시망막후도，수방3mo，관찰량조적료효。 　　결과：연합조재치료3 mo후총유효솔체도82％，가감주경방조총유효솔체도60％；연합조재치료3 mo후안저출혈흡수총유효솔체88％，가감주경방조적유효솔체64％；재강저중심시망막후도방면，각조치료후여치료전비교급량조조간비교，차이균유통계학의의（P＜0．05）。 　　결론：중약가감주경방능유효지연완병정적발전、감소병변적반복차수급제고환자적시력。
AIM: To investigate the clinical effect of Modified Zhujing Formula combined with Lucentis on treating macular hemorrhage of pathological myopia. METHODS: Forty-two patients (42 eyes) were divided into 2 groups:Modified Zhu Jing Formula group, 25 cases (25 eyes), were treated with Modified Zhu Jing Formula, and combined treatment group administrated Modified Zhu Jing Formula with intravitreal Lucentis injection ( 17 eyes in 17 cases) .Central retinal thickness was measured by optical coherence tomography before and after the treatment. Three months after the treatment, the therapeutic effect was observed. RESULTS: Three months after the treatment, the total effective rate of combined treatment group was 82%, while that of Modified Zhu Jing Formula group was 60%. The total effective rate of fundus hemorrhage absorption for combined treatment group was 88%, while that of Modified Zhu Jing Formula group was 64%.In terms of reducing central retinal thickness, the difference between pre-treatment and post-treatment for each group and the difference between two groups were both significant ( P<0.05). CONCLUSION: Modified Zhu Jing Formula can slow down disease progression, decrease recurrent risk and improve patients'vision.