国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
2期
307-309
,共3页
胡正再%张思文%欧阳红专%李琳
鬍正再%張思文%歐暘紅專%李琳
호정재%장사문%구양홍전%리림
微角膜刀%前弹力层下角膜磨镶术%角膜混浊
微角膜刀%前彈力層下角膜磨鑲術%角膜混濁
미각막도%전탄력층하각막마양술%각막혼탁
microkeratome%sub - Bowman keratomileusis%corneal opacity
目的：筛选引起机械微角膜刀前弹力层下角膜磨镶术（ sub-Bowman keratomileusis ，SBK）后角膜混浊的相关因素，为优化SBK术后效果提供参考。<br> 方法：回顾性病例研究。法国Moria公司OUP90刀头制瓣的SBK术后896眼，术后3 mo复查，记录有无角膜混浊。根据角膜混浊与否分为两组，对两组性别、年龄、术前眼压、术前角膜中央厚度、K1、K2、平均角膜曲率、术前等效球镜值进行统计学分析。<br> 结果：角膜混浊组男52眼，女48眼，年龄（24．5±6．1）岁，眼压（14．26±2．24）mmHg，角膜中央厚度（487．27±18．52）μm， K1（44．24±1．23）D，K2（43．33±1．13）D，平均曲率（43．79±1．15）D，等效球镜度（-4．65±1．44）D；角膜无混浊组男412眼，女384眼，年龄（24．3±5．8）岁，眼压（16．72±7.01） mmHg，角膜中央厚度（533．11±28．74）μm， K1（43.90±1．47）D，K2（42．88±1．35）D，平均曲率（43．39±1.37）D，等效球镜度（-5．04±1．96）D；两组中性别（χ2＝0．002，P＝0．964）、年龄（t＝0．404，P＝0．686）、等效球镜度（t ＝1．949，P＝0．052）差异无统计学意义；而术前眼压（t＝-3．486，P＝0．001）、术前角膜中央厚度（ t＝-15．543，P＝0.000）、K1（t ＝2．249，P＝0．025）、K2（t ＝3．172，P＝0.002）及平均角膜曲率（ t ＝2．763， P ＝0．006）差异有统计学意义。<br> 结论：术前中央角膜薄、眼压低、角膜曲率高者机械刀SBK术后角膜混浊发生率高，性别、年龄、术前屈光度与机械刀SBK术后角膜混浊无关。
目的：篩選引起機械微角膜刀前彈力層下角膜磨鑲術（ sub-Bowman keratomileusis ，SBK）後角膜混濁的相關因素，為優化SBK術後效果提供參攷。<br> 方法：迴顧性病例研究。法國Moria公司OUP90刀頭製瓣的SBK術後896眼，術後3 mo複查，記錄有無角膜混濁。根據角膜混濁與否分為兩組，對兩組性彆、年齡、術前眼壓、術前角膜中央厚度、K1、K2、平均角膜麯率、術前等效毬鏡值進行統計學分析。<br> 結果：角膜混濁組男52眼，女48眼，年齡（24．5±6．1）歲，眼壓（14．26±2．24）mmHg，角膜中央厚度（487．27±18．52）μm， K1（44．24±1．23）D，K2（43．33±1．13）D，平均麯率（43．79±1．15）D，等效毬鏡度（-4．65±1．44）D；角膜無混濁組男412眼，女384眼，年齡（24．3±5．8）歲，眼壓（16．72±7.01） mmHg，角膜中央厚度（533．11±28．74）μm， K1（43.90±1．47）D，K2（42．88±1．35）D，平均麯率（43．39±1.37）D，等效毬鏡度（-5．04±1．96）D；兩組中性彆（χ2＝0．002，P＝0．964）、年齡（t＝0．404，P＝0．686）、等效毬鏡度（t ＝1．949，P＝0．052）差異無統計學意義；而術前眼壓（t＝-3．486，P＝0．001）、術前角膜中央厚度（ t＝-15．543，P＝0.000）、K1（t ＝2．249，P＝0．025）、K2（t ＝3．172，P＝0.002）及平均角膜麯率（ t ＝2．763， P ＝0．006）差異有統計學意義。<br> 結論：術前中央角膜薄、眼壓低、角膜麯率高者機械刀SBK術後角膜混濁髮生率高，性彆、年齡、術前屈光度與機械刀SBK術後角膜混濁無關。
목적：사선인기궤계미각막도전탄력층하각막마양술（ sub-Bowman keratomileusis ，SBK）후각막혼탁적상관인소，위우화SBK술후효과제공삼고。<br> 방법：회고성병례연구。법국Moria공사OUP90도두제판적SBK술후896안，술후3 mo복사，기록유무각막혼탁。근거각막혼탁여부분위량조，대량조성별、년령、술전안압、술전각막중앙후도、K1、K2、평균각막곡솔、술전등효구경치진행통계학분석。<br> 결과：각막혼탁조남52안，녀48안，년령（24．5±6．1）세，안압（14．26±2．24）mmHg，각막중앙후도（487．27±18．52）μm， K1（44．24±1．23）D，K2（43．33±1．13）D，평균곡솔（43．79±1．15）D，등효구경도（-4．65±1．44）D；각막무혼탁조남412안，녀384안，년령（24．3±5．8）세，안압（16．72±7.01） mmHg，각막중앙후도（533．11±28．74）μm， K1（43.90±1．47）D，K2（42．88±1．35）D，평균곡솔（43．39±1.37）D，등효구경도（-5．04±1．96）D；량조중성별（χ2＝0．002，P＝0．964）、년령（t＝0．404，P＝0．686）、등효구경도（t ＝1．949，P＝0．052）차이무통계학의의；이술전안압（t＝-3．486，P＝0．001）、술전각막중앙후도（ t＝-15．543，P＝0.000）、K1（t ＝2．249，P＝0．025）、K2（t ＝3．172，P＝0.002）급평균각막곡솔（ t ＝2．763， P ＝0．006）차이유통계학의의。<br> 결론：술전중앙각막박、안압저、각막곡솔고자궤계도SBK술후각막혼탁발생솔고，성별、년령、술전굴광도여궤계도SBK술후각막혼탁무관。
AIM: To provide a reference to improve postoperative effects by screening the related factors causing corneal opacity after sub-Bowman keratomileusis ( SBK ) by mechanical microkeratome. <br> METHODS: In this retrospective cases study, 896 eyes underwent sub-Bowman keratomileusis with and they were followed up for 3mo postoperatively.Record was made on whether the corneal opacity occurred. These eyes were divided into 2 groups corneal opacity group and clear cornea group. The gender, age, preoperative intraocular pressure ( IOP ) , preoperative central cornea thickness (CCT), K1, K2, mean K, preoperative spherical equivalent ( SE) were statistically analyzed. <br> RESULTS:There were 52 males and 48 females in haze group, mean age were (24.5±6.1)year, preoperative IOP were (14.26±2.24)mmHg, preoperative CCT were (487.37± 18.52)μm, K1, K2, mean K were (44.24±1.23)D, (43.33± 1.13 ) D, ( 43.79 ±1.15 ) D, respectively, preoperative SE were (-4.65 ±1.44 ) D.There were 412 males and 384 females in without haze group, mean age were ( 24.3 ± 5.8) year, preoperative IOP were ( 16.72 ±7.01 ) mmHg, preoperative CCT were (533.11±28.74)μm, K1 , K2 , mean K were (43.90±1.47)D, (42.88±1.35)D, (43.39±1.37)D, respectively, preoperative SE were (-5.04±1.96)D.The difference of sex (χ2=0.002, P=0.964), age (t=0.404, P=0.686), preoperative SE (t=1.949, P=0.052) between the 2 groups were insignificant. The difference of preoperative IOP (t=-3.486, P=0.001), preoperative CCT (t=-15.543, P=0.000), K1(t=2.249, P=0.025), K2(t=3.172, P=0.002), mean K (t=2.763, P=0.006) between the two groups of haze after mechanical microkeratome SBK. <br> CONCLUSION:The incidence of corneal opacity is high in patients with thin preoperative CCT, low IOP and high corneal curvature after SBK surgery by microkeratome. Gender, age and preoperative spherical equivalent are not related to the incidence of corneal opacity after SBK surgery.
