当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
2期
153-154
,共2页
肺炎支原体肺炎%阿奇霉素%红霉素
肺炎支原體肺炎%阿奇黴素%紅黴素
폐염지원체폐염%아기매소%홍매소
Mycoplasma pneumonia%Azithromycin%Erythromycin
目的：比较阿奇霉素与红霉素治疗小儿肺炎的临床效果。方法选取120例肺炎支原体肺炎的儿童患者，随机分为两组即阿奇霉素组和红霉素组，各60例，分别采用阿奇霉素和红霉素治疗10 d，阿奇霉素组采用阿奇霉素静脉注射4 d，1次/d，12 mg/（kg·d），后口服阿奇霉素片6 d，0.25 g/片，2次/d，红霉素组采用红霉素静脉注射4 d，12 mg/次，1次/d，后口服红霉素6 d，0.25 g/片，2次/d，观察两种治疗方法的临床效果。结果治疗后，阿奇霉素组总有效率为98.33%，明显高于红霉素组的71.67%；阿奇霉素组患儿发热消失时间、咳嗽消失时间、肺啰音消失时间明显优于红霉素组。阿奇霉素组不良反应发生率6.67%，明显低于红霉素组的31.67%，差异均有统计学意义（P<0.05）。结论阿奇霉素比红霉素治疗小儿肺炎支原体肺炎更能改善临床症状，使肺部阴影尽快吸收，恢复肺部正常功能，治疗效果显著。
目的：比較阿奇黴素與紅黴素治療小兒肺炎的臨床效果。方法選取120例肺炎支原體肺炎的兒童患者，隨機分為兩組即阿奇黴素組和紅黴素組，各60例，分彆採用阿奇黴素和紅黴素治療10 d，阿奇黴素組採用阿奇黴素靜脈註射4 d，1次/d，12 mg/（kg·d），後口服阿奇黴素片6 d，0.25 g/片，2次/d，紅黴素組採用紅黴素靜脈註射4 d，12 mg/次，1次/d，後口服紅黴素6 d，0.25 g/片，2次/d，觀察兩種治療方法的臨床效果。結果治療後，阿奇黴素組總有效率為98.33%，明顯高于紅黴素組的71.67%；阿奇黴素組患兒髮熱消失時間、咳嗽消失時間、肺啰音消失時間明顯優于紅黴素組。阿奇黴素組不良反應髮生率6.67%，明顯低于紅黴素組的31.67%，差異均有統計學意義（P<0.05）。結論阿奇黴素比紅黴素治療小兒肺炎支原體肺炎更能改善臨床癥狀，使肺部陰影儘快吸收，恢複肺部正常功能，治療效果顯著。
목적：비교아기매소여홍매소치료소인폐염적림상효과。방법선취120례폐염지원체폐염적인동환자，수궤분위량조즉아기매소조화홍매소조，각60례，분별채용아기매소화홍매소치료10 d，아기매소조채용아기매소정맥주사4 d，1차/d，12 mg/（kg·d），후구복아기매소편6 d，0.25 g/편，2차/d，홍매소조채용홍매소정맥주사4 d，12 mg/차，1차/d，후구복홍매소6 d，0.25 g/편，2차/d，관찰량충치료방법적림상효과。결과치료후，아기매소조총유효솔위98.33%，명현고우홍매소조적71.67%；아기매소조환인발열소실시간、해수소실시간、폐라음소실시간명현우우홍매소조。아기매소조불량반응발생솔6.67%，명현저우홍매소조적31.67%，차이균유통계학의의（P<0.05）。결론아기매소비홍매소치료소인폐염지원체폐염경능개선림상증상，사폐부음영진쾌흡수，회복폐부정상공능，치료효과현저。
Objective To compare the clinical effects of azithromycin and erythromycin in the treatment of pediatric pneumonia. Methods 120 cases of pediatric patients with mycoplasma pneumonia treated in the hospital were randomly divided into two groups, that was azithromycin group and erythromycin group,60 cases in each group;azithromycin and erythromycin were used for 10 days respectively,azithromycin group used intravenous injection of azithromycin for four days,one time each day,12 mg/(kg?d),then adopted oral azithromycin tablet for six days,0.25 g/tablet,two times each day.Erythromycin used intravenous injection of erythromycin for four days,one time each day,and 12 mg every time,then adopted oral erythromycin for six days,0.25 mg/tablet,two times everyday. the clinical effects of two treatment methods were observed. Results After treatment, the total effective rate of azithromycin group (98.33%) was significantly higher than the erythromycin group (71.67%), the disappearance time of fever, cough and pulmonary rales of azithromycin group were significantly shorter than erythromycin group,and the incidence of adverse reactions in azithromycin group (6.67%) was significantly less than that in erythromycin group (31.67%), it was statistically significant (P<0.05). Conclusion Azithromycin can improve the clinical symptoms better than erythromycin in the treatment of mycoplasma pneumonia, and the pulmonary shadows are absorbed as soon as possible ,the function of lungs restore to normal ,with significant treatment effect.
