CAJ | 학술논문

目的：比较腹腔镜下子宫次全切除术与开腹子宫次全切除术对患者机体的组织损伤。方法选择因子宫肌瘤就诊选择腹腔镜子宫次全切除术的30例患者作为研究组（腹腔镜组）。随机抽取同期选择开腹子宫次全切除术的30例患者作为对照组（开腹组）。比较两组患者术前1 d、术后1d、术后3d外周静脉血C反应蛋白、肿瘤坏死因子α、白细胞数，同时比较两组术中、术后情况。结果腹腔镜组术后1d、术后3d的白细胞数分别为：（8.70±1.22）×109/L，（6.83±1.39）×109/L，术后1 d、术后3 d的C反应蛋白数值分别为：（13.97±5.19）mg/L，（7.63±3.43）mg/L，术后1 d、术后3 d的肿瘤坏死因子α数值分别为：（61.69±12.78）pg/mL,（64.86±9.15）pg/mL变化程度均小于开腹手术。与开腹组相比，腹腔镜组术中出血量少、术后排气时间早、住院时间短。结论腹腔镜下子宫次全切术较开腹子宫次全切除术组织损伤小，有利于局部及全身损伤的恢复。
목적：비교복강경하자궁차전절제술여개복자궁차전절제술대환자궤체적조직손상。방법선택인자궁기류취진선택복강경자궁차전절제술적30례환자작위연구조（복강경조）。수궤추취동기선택개복자궁차전절제술적30례환자작위대조조（개복조）。비교량조환자술전1 d、술후1d、술후3d외주정맥혈C반응단백、종류배사인자α、백세포수，동시비교량조술중、술후정황。결과복강경조술후1d、술후3d적백세포수분별위：（8.70±1.22）×109/L，（6.83±1.39）×109/L，술후1 d、술후3 d적C반응단백수치분별위：（13.97±5.19）mg/L，（7.63±3.43）mg/L，술후1 d、술후3 d적종류배사인자α수치분별위：（61.69±12.78）pg/mL,（64.86±9.15）pg/mL변화정도균소우개복수술。여개복조상비，복강경조술중출혈량소、술후배기시간조、주원시간단。결론복강경하자궁차전절술교개복자궁차전절제술조직손상소，유리우국부급전신손상적회복。
Objective To explore the effect of laparoscopic subtotal hysterectomy on the tissue trauma in patients with myoma of uterus required to operation. Methods The patients with myoma of uterus were devided into laparoscopic groups and open operation group. The WBC count,neutrophil proportion rate,C reaction protein and tumor necrosis factor-αlevels were in peripheral blood at preoperative 1 day, postoperative 1 day and 3 days were measured and compared. Results The damage factors we chose were lower significantly after laparoscopic surgery than the open operation group. Conclusion Laparoscopic surgery has a more favorable clinical outcome because of less tissue trauma.