CAJ | 학술논문

目的：探讨四川遂宁地区儿童铜绿假单胞菌（PA ）的临床专业分布及耐药谱的变迁，为临床合理选用抗菌药物提供依据。方法应用ATB细菌鉴定药敏系统鉴定细菌，K-B法做药敏试验，统计分析该院2010～2012年PA的检出情况、儿科各专业的分布情况和耐药情况。结果46株PA主要分布在呼吸、新生儿和重症医学专业，共39株（84．8％）。来自痰液标本共22株（47．83％）。3年来的分离率及对抗菌药物的耐药性逐年增加。结论 PA是临床感染的主要致病菌之一，应对其加强耐药性监测，合理使用抗菌药物。
목적：탐토사천수저지구인동동록가단포균（PA ）적림상전업분포급내약보적변천，위림상합리선용항균약물제공의거。방법응용ATB세균감정약민계통감정세균，K-B법주약민시험，통계분석해원2010～2012년PA적검출정황、인과각전업적분포정황화내약정황。결과46주PA주요분포재호흡、신생인화중증의학전업，공39주（84．8％）。래자담액표본공22주（47．83％）。3년래적분리솔급대항균약물적내약성축년증가。결론 PA시림상감염적주요치병균지일，응대기가강내약성감측，합리사용항균약물。
Objective To investigate the distribution status of Pseudomonas aeruginosa (PA) in children in Suining area and the changes of drug-resistance spectrum to provide the basis for clinical antibacterial drugs selection .Methods The ATB microbiologi-cal system was adopted to identify the bacteria and the K-B method was used to conduct the drug sensitivity test .The detection situ-ation of PA in our hospital from January 2010 to December 2012 was performed the statistical analysis on the distribution in various specialties of pediatrics and drug resistance .Results Among 46 isolated strains of PA ,39 strains were mainly distributed in the specialties of respiration ,neonatology and pediatric intensive care unit (PICU) ,which accounted for 84 .8 % ,22 strains were isolated from sputum specimens ,which accounted for 47 .83% .The isolation rate in last three years showed the rising trend year by year , and the resistance to antibiotics was increased year after year .Conclusion PA is one of the main pathogens of clinical infection .We should strengthen its drug-resistance monitoring and use antibacterial drugs reasonably .